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第18章放线菌属与诺卡菌属第一节放线菌属一、生物学性状G+,丝状菌,可缠绕成团,非抗酸菌,产抗生素培养比较困难,厌氧或微需氧,培养时间较长(5天左右),液体混浊病灶中可以形成菊花形的硫磺颗粒,Sulfurgranulesarecharacteristicallyfoundinpusfromlesionsandarediagnostic(actuallyamassofActinomycesfilamentssolidifiedwithtissueexudates.From:MaryT.Johnson,Ph.D.IndianaUniversitySchoolofMedicine,Cervicofacialactinomycosis:suppurativereactionoftheinfectionmaydischargelargeyellowflecksthatarecoloniesofbacteria(sulfurgranules)Etiology:ActinomycesIsraeliiorA.viscosusorganisms.From:www.dental.mu.edu,二、致病性,放线菌大多属于正常菌群,寄居口腔等、可以成为条件致病菌(衣氏放线菌)放线菌病:特点:脓肿、多发性瘘管、脓汁中有硫磺颗粒,好发于面颈部.,ActinomycosesFrom:http:/faculty.plattsburgh.edu,Cervicofacialactinomycosis:suppurativereactionoftheinfectionmaydischargelargeyellowflecksthatarecoloniesofbacteria(sulfurgranules)Etiology:ActinomycesIsraeliiorA.viscosusorganisms.From:www.dental.mu.edu,放线菌与龋齿和牙周炎有关。内氏放线菌,粘液放线菌-产生6-去氧太洛糖-使其它细菌粘附于牙釉质表面-菌斑-产酸-龋齿。其他细菌的进一步侵入:引起牙龈炎,牙周炎,第二节诺卡菌属G+丝状菌(末端不膨大)专性需氧,营养要求不高,生长缓慢液体菌膜平板黄白色R型菌落主要分布于土壤中,不属于人体正常菌群引起化脓性感染(免疫功能低下者)特点:化脓、坏死、结节、瘘管,对人致病的主要有:星形、巴西诺卡菌,Colonysurfacesappearroughastheyadherestronglytotheagarbaseduetotheinbeddedbranchingfilamentsandanorangetoredpigmentmaydevelop.http:/education.med.nyu.edu,2020/4/30,医学微生物学,From:MaryT.Johnson,Ph.D.IndianaUniversitySchoolofMedicine,CT,
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