支气管哮喘英文版课件

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,Bronchial asthma,Department of respiration,Kong lingfei,Bronchial asthma,1,Asthma i human killer/,Asthma i human killer/,2,Background of asthma,Prevalence in the world: 1.6 hundred million,in China:1-3,in Shenyang: 1.24 %(1999),GINA: Global Initiative for Asthma (1994,WHO /HLBI,Bronchial asthmatic diagnosis guideline( 1997,Chinese medical academy,Background of asthma,3,Definitions of asthma,Chronic airway inflammation,Broncho-hyperresponsiveness BHR,Airflow limitation,Definitions of asthma,4,Mechanism: allergy theory,antigen,antigen,atopy IgE antibody mast cells., basophils,histamine,inflammatory mediaLTs,PAF,ECP,immediate asthmatic reaction, IAR,bronchial smooth muscle spasm,airway narrow,Mechanism: allergy theory,5,Mechanism: never-receptor disorder theory,adrenergic and cholinergic nerous systems, AC,non-adrenergic and non-cholinergic nerous systems, NANC,AC: al-receptor, MI, M3-receptors ) excitement,NANC: PS-receptor,bronchial smooth muscle contraction,AC: receptor、 M2-receptor,excitement,NANC: VIP receptor,bronchial smooth muscle dilation,asthmatic airway:al、M1、M3、PS/、M2、VP,Mechanism: never-receptor diso,6,Mechanism: airway inflammation theory,antigen,allergic airway inflammation AAI,ECP,MBP,inflammatory cells inflammatory mediaLTs,EOS,PAF,neutrophils,late asthmatic reaction. LAR,Tlymphocyte(Thi/Th2D),Th2 cytokine Il3、4、5, GM-CSFlgE,Mechanism: airway inflammation,7,Differ mechanisms in acute and chronic asthma,acute,chronic,inflammation,inflammation,remodelling,bronchial contraction,inflammation cells,cell proliferation,mucous edema,epithelium injury,airway secretion,excellular base,aIrway,aIrway narrow,BHR,reversibility,symptoms,exacerbation,Differ mechanisms in acute and,8,Other mechanisms: induced factors,Allergen: pollen, acarus,infection: virus or mycoplasmal infection,climate and physical and chemical factors,drugs: aspirin induced asthma, AIA,- receptor inhibitor,heredity,Gastroesophageal reflux disease GERD,Psychological, incretion factors, sports,Other mechanisms: induced fact,9,Diagnosis standards of asthma,symptoms,signs,recovered ways,except other cardiac and pulmonary diseases,lung function examination untypical asthma,Diagnosis standards of asthma,10,支气管哮喘英文版课件,11,支气管哮喘英文版课件,12,支气管哮喘英文版课件,13,支气管哮喘英文版课件,14,支气管哮喘英文版课件,15,支气管哮喘英文版课件,16,支气管哮喘英文版课件,17,支气管哮喘英文版课件,18,支气管哮喘英文版课件,19,支气管哮喘英文版课件,20,支气管哮喘英文版课件,21,支气管哮喘英文版课件,22,支气管哮喘英文版课件,23,支气管哮喘英文版课件,24,支气管哮喘英文版课件,25,支气管哮喘英文版课件,26,支气管哮喘英文版课件,27,支气管哮喘英文版课件,28,支气管哮喘英文版课件,29,支气管哮喘英文版课件,30,支气管哮喘英文版课件,31,支气管哮喘英文版课件,32,支气管哮喘英文版课件,33,支气管哮喘英文版课件,34,支气管哮喘英文版课件,35,支气管哮喘英文版课件,36,支气管哮喘英文版课件,37,支气管哮喘英文版课件,38,支气管哮喘英文版课件,39,支气管哮喘英文版课件,40,支气管哮喘英文版课件,41,