【病毒外文文献】2010 Type I canine enteric coronavirus reported at a low prevalence in dogs in the UK

54 Veterinary Record January 9 2010 Research DigestResearch Digest Selected highlights from other veterinary journals Research Digest Assessing the prevalence and welfare implications of inherited disorders in pedigree dogs J F Summers G Diesel L Asher P D McGreevy L M Collins The number and severity of inherited disorders with no apparent link to conformation were examined in pedigree dogs in the second part of a study that reviewed the impact of breeding for particular characteristics on the welfare of a breed part one studied conformation linked disorders related to breed standards and is summarised in VR January 2 2010 vol 166 p 26 Information was compiled from a literature review of the top 50 Kennel Club registered breeds in the UK and included details of the body systems affected A six level grading system the strength of evidence for hereditary basis scale SehB was developed to compare the quality of available evidence on the heritability of a disease The generic illness severity index for dogs GSID was used to score and compare the impact of different disorders on the health and welfare of a breed A total of 312 inherited disorders were identified with the majority being inherited in an autosomal recessive manner The breed found to be susceptible to the most disorders 58 different disorders was the German shepherd dog Disorders affecting the largest number of breeds were hypothyroidism 43 breeds hereditary adult onset cataract 38 breeds and progressive retinal atrophy 35 breeds scores for the possible severity of these diseases were shown to range widely for different breeds The body system most affected was the nervous sensory system The authors identified a lack of reliable country specific prevalence data for inherited diseases in the dog population in individual breeds and in crossbreeds for comparison to pedigree populations Future research would allow a quantitative assessment of the welfare impact of inherited disorders on the pedigree dog population in the UK Veterinary Journal 2010 183 39 45 doi 10 1016 j tvjl 2009 11 002 doi 10 1136 vr c51 Providing an accurate faecal egg count in horses analysis of faecal sample storage M K Nielsen A N Vidyashankar U V Andersen K DeLisi K Pilegaard R M Kaplan STronGylID egg counts are gaining increasing importance for monitoring parasite infection and anthelmintic resistance in horses The effects of storage on faecal egg count FeC measurements may therefore be important in obtaining accurate and comparable results and the identification of procedures that could be implemented as best practice are therefore warranted This study measured the effects of storage temperature time and type of container on FeC Faecal samples from a horse determined to be shedding 200 to 500 epg were collected rectally and stored in an airtight container in one of four temperature dependent locations a freezer refrigerator incubator or at room temperature In another experiment samples were stored on the floor of a stable in either an airtight container or left in the open air FeC was measured at successive times following storage The study was conducted in two separate locations at different times of year in Georgia USA during June and July and Copenhagen Denmark in november At both locations samples kept in the refrigerator showed no decline in FeC compared with samples stored in the freezer or incubator which showed a decrease in FeC over time At room temperature FeC remained stable in samples from the USA but showed a significant decrease in samples from Denmark after 24 hours In the USA samples left in the open air showed a significant decline in FeC compared to those stored in an airtight container after 12 hours whereas in Denmark no differences were shown between airtight and open air storage this was attributed to the different temperatures in the two countries refrigeration was shown to be the best storage method for faecal samples however accurate results could also be obtained from faecal samples collected from the ground within 12 hours Veterinary Parasitology 2010 167 55 61 doi 10 1016 j vetpar 2009 09 043 doi 10 1136 vr c53 Type I canine enteric coronavirus reported at a low prevalence in dogs in the UK J Stavisky G L Pinchbeck A J German S Dawson R M Gaskell R Ryvar A D Radford CAnIne enteric coronavirus CeCoV is a pathogen commonly found in dogs which has been shown to exist in two closely related forms infection may occur from one or both strains As there is limited data on the prevalence of CeCoV and commercial diagnostic tests suitable for distinction between the two virus strains are not widely available this study aimed to investigate the carriage of types I and II CeCoV in the dog population in the UK Twenty veterinary practices randomly chosen from across the UK were asked to pick dogs presented to the practice for any reason to reflect the clientele and caseload of the practice The final sample included 249 dogs with a mean of 12 dogs per practice The majority of dogs 144 were from single dog households A faecal sample was obtained from each dog and a brief questionnaire was used to record demographic and clinical data on the animal which included any recent history of enteric disease Samples were tested by rT PCr for the presence of CeCoV A low prevalence 2 8 per cent of CeCoV was found with seven of the 249 samples being positive for the virus Three positive samples were obtained from dogs in the same household The four other positive results were from dogs from a wide geographical distribution and three of these were shown to have had a history of diarrhoea in the previous month Five of the dogs were aged six years or more and the authors suggest that older dogs may play a role in the persistence of the virus in a population Sequencing of the virus showed all positive samples to be type I CeCoV the first report of this virus strain in the UK Veterinary Microbiology 2010 140 18 24 doi 10 1016 j vetmic 2009 07 012 doi 10 1136 vr c52 54 Research digest indd 54 6 1 10 15 47 06 on March 10 2015 Published by from a low prevalence in dogs in the UK Type I canine enteric coronavirus reported at Ryvar and A D Radford J Stavisky G L Pinchbeck A J German S Dawson R M Gaskell R doi 10 1136 vr c52 2010 166 54 Veterinary Record Updated information and services can be found at These include service Email alerting box at the top right corner of the online article Receive free email alerts when new articles cite this article Sign up in the Notes To request permissions go to To order reprints go to To subscribe to BMJ go to on March 10 2015 Published by from