骨质疏松症诊断和治疗课件

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,骨质疏松症诊断和治疗,s,(,宣城市中医院骨科,Eat high-calcium foods, exercise regularly,nd do not smoke at young age to prevent,裴四才,骨质疏松症诊断和治疗,1,主要内容,骨概述,骨质疏松症基本概念,骨质疏松症的临床表现,骨质疏松症的诊断与鉴别诊断,骨质疏松症的防治,主要内容,2,骨代谢疾病,骨是一种特殊的结缔组织,是坚硬而,有生命、始终进行着代谢活动的组织。,所有能导致全身骨质代谢及钙磷代谢,紊乱的因素,均可造成全身性弥漫性的骨,骼损害一即代谢性骨病。,骨代谢疾病,3,骨的构造,密质骨(皮质骨,松质骨(小梁骨),Cancello,one,骨的构造,4,正常,骨质疏松,严重骨质疏松,Courtesy Dr, A. Boyde,正常,5,主要内容,骨概述,骨质疏松症基本概念,骨质疏松症的临床表现,骨质疏松症的诊断与鉴别诊断,骨质疏松症的防治,主要内容,6,1994年0定义:,骨质疏松症是一种全身性代谢性骨病,以骨量减少、骨的微结构破坏为特征,导,致骨的脆性增加,容易发生骨折。,1994年0定义:,7,骨质疏松症目前的定义,以骨强度受损导致骨折危险性升高为特征的骨骼,疾病。骨强度主要反映了骨密度和骨质量两个方面,的综合特征。,正常骨,骨质疏松骨,NIH Consensus Development Panel on Osteoporosis. JAMA 285 (2019): 785-95,骨质疏松症目前的定义,8,骨质疏松损害骨强度,增加骨折的危险性,骨强度=骨质量0%+骨密度%0,几何学和微结构,2.骨转换率,BMD g/cm2,3.矿化程度,VBMD= g/cm,4.损伤累积,5.基质/胶原质量,Adapted from NIH Consensus Development Panel on Osteoporosis. JAMA 2019,骨质疏松损害骨强度,9,结构的影响,质量和,数量减少,数量减少,结构均正常,结构丧失,结构的影响,10,骨质疏松症诊断和治疗课件,11,骨质疏松症诊断和治疗课件,12,骨质疏松症诊断和治疗课件,13,骨质疏松症诊断和治疗课件,14,骨质疏松症诊断和治疗课件,15,骨质疏松症诊断和治疗课件,16,骨质疏松症诊断和治疗课件,17,骨质疏松症诊断和治疗课件,18,骨质疏松症诊断和治疗课件,19,骨质疏松症诊断和治疗课件,20,骨质疏松症诊断和治疗课件,21,骨质疏松症诊断和治疗课件,22,骨质疏松症诊断和治疗课件,23,骨质疏松症诊断和治疗课件,24,骨质疏松症诊断和治疗课件,25,骨质疏松症诊断和治疗课件,26,骨质疏松症诊断和治疗课件,27,骨质疏松症诊断和治疗课件,28,骨质疏松症诊断和治疗课件,29,骨质疏松症诊断和治疗课件,30,骨质疏松症诊断和治疗课件,31,骨质疏松症诊断和治疗课件,32,骨质疏松症诊断和治疗课件,33,骨质疏松症诊断和治疗课件,34,骨质疏松症诊断和治疗课件,35,骨质疏松症诊断和治疗课件,36,骨质疏松症诊断和治疗课件,37,骨质疏松症诊断和治疗课件,38,骨质疏松症诊断和治疗课件,39,骨质疏松症诊断和治疗课件,40,骨质疏松症诊断和治疗课件,41,骨质疏松症诊断和治疗课件,42,骨质疏松症诊断和治疗课件,43,骨质疏松症诊断和治疗课件,44,骨质疏松症诊断和治疗课件,45,骨质疏松症诊断和治疗课件,46,骨质疏松症诊断和治疗课件,47,骨质疏松症诊断和治疗课件,48,骨质疏松症诊断和治疗课件,49,骨质疏松症诊断和治疗课件,50,骨质疏松症诊断和治疗课件,51,骨质疏松症诊断和治疗课件,52,骨质疏松症诊断和治疗课件,53,骨质疏松症诊断和治疗课件,54,骨质疏松症诊断和治疗课件,55,骨质疏松症诊断和治疗课件,56,骨质疏松症诊断和治疗课件,57,骨质疏松症诊断和治疗课件,58,骨质疏松症诊断和治疗课件,59,骨质疏松症诊断和治疗课件,60,骨质疏松症诊断和治疗课件,61,骨质疏松症诊断和治疗课件,62,骨质疏松症诊断和治疗课件,63,骨质疏松症诊断和治疗课件,64,骨质疏松症诊断和治疗课件,65,骨质疏松症诊断和治疗课件,66,骨质疏松症诊断和治疗课件,67,骨质疏松症诊断和治疗课件,68,骨质疏松症诊断和治疗课件,69,骨质疏松症诊断和治疗课件,70,骨质疏松症诊断和治疗课件,71,骨质疏松症诊断和治疗课件,72,骨质疏松症诊断和治疗课件,73,骨质疏松症诊断和治疗课件,74,骨质疏松症诊断和治疗课件,75,骨质疏松症诊断和治疗课件,76,骨质疏松症诊断和治疗课件,77,