睾丸肿瘤Neoplasms-of-the-Testis介绍

Incidence-3.7 per 100,000 (USA 1971) 隐睾(cryptorchidism) 5-10% 遗传(genetic factors) 2-3% 损伤(trauma) 、氧化锌 萎缩(atrophy) l原发(Primary neoplasms)： 生殖细胞肿瘤(germinal neoplasms) 精原细胞瘤(seminoma) 胚胎瘤(embryonal carcinoma) 畸胎瘤(teratoma) 绒毛膜上皮瘤(choriocarcinoma) 非生殖细胞肿瘤(nongerminal neoplasms) 性腺基质肿瘤(gonadal stromal neoplasms)l继发(Secondary)： 恶性淋巴瘤(metastases) l A nodule or painless swelling or harden of one gonadl In approximately 10% of patients,acute pain is the presenting symptoml In approximately 10% of patients,metastases symptom is the present l Historyl Physical examinationl Lab examination 瘤标(tumor markers)： -FP (+) 胚胎瘤 hCG (+) 精原细胞瘤 、绒毛膜上皮癌 LDH 乳酸脱氢酶、PALA胎盘碱性磷酸酶l Ultrasonography Surgery: radical orchiectomy根治性睾丸切除术l Seminoma（精原细胞瘤） radical orchiectomy+radiation therapy。l Embryonal carcinoma(胚胎癌) radical orchiectomy +retroperitoneal lymphadenectomy(腹膜后淋巴结清扫术)l Choriocarcinoma(绒毛膜上皮癌) radical orchiectomy +chemotherapy l现代泌尿外科肿瘤学 顾方六主编, 科学出版社,2003l Cambells Urology, eight edition, W.B. Sunders company,2003l中华泌尿外科杂志l Journal of Urology