青光眼滤过手术抗瘢痕的药物研究进展课件

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,Recent advances in,anti-fibrosis agents,for glaucoma filtration,surgery,Author liuziming,Recent advances in,1,ev words,filtration anti-fibrosis,glaucoma,TGF-B,surgery,agent,ev words,2,Abstract,Glaucoma filtration surgery usually fails due to,postoperative scarring,From 1980s. a large number of researches have,been performing on anti-fibrosis agents to,secure the success of the operation,These agents play a certain role in improving,filtration function, reducing intraocular pressure,and increasing the rate of success,Anti-fibrosis agents which have been studied are,reviewed here, and new ways which have,potential value are also discussed in this article,Abstract,3,青光眼滤过手术目的,术后应可看到弥漫、无血管、水汪汪的功,能性滤过泡,但是部分患者滤过泡扁平,滤过区看不到隆起的滤过泡,青光眼滤过手术目的,4,梁切除术后滤讨洧弥散,充血轻微,梁切除术后滤讨洧弥散,充血轻微,5,小梁切除术后非功能性滤过泡,扁平疤痕化,充,小梁切除术后非功能性滤过泡,扁平疤痕化,充,6,:、自:sE,3:3,(IX23C7DI,正常滤过泡BM表现,疤痕滤过泡UBM表现,为低回声液性暗区,为高回声实性暗区,:、自:sE,7,滤过性手术是目前治疗青光眼的一种最常,用方法,但手术后2年失败率可以高达15,25%1,手术区滤过口处成纤维细胞增殖,瘢痕形,成而使滤过泡失去滤过功能是手术失败的,主要原因。,目前,许多学者在抗纤维化药物方面作了,许多研究,现作如下综述,滤过性手术是目前治疗青光眼的一种最常,8,1抗代谢药物,2抗凝血药,1抗代谢药物,9,抗代谢药物,5-FU,MMC,HHT,Cs A,others,抗代谢药物,10,青光眼滤过手术抗瘢痕的药物研究进展课件,11,青光眼滤过手术抗瘢痕的药物研究进展课件,12,青光眼滤过手术抗瘢痕的药物研究进展课件,13,青光眼滤过手术抗瘢痕的药物研究进展课件,14,青光眼滤过手术抗瘢痕的药物研究进展课件,15,青光眼滤过手术抗瘢痕的药物研究进展课件,16,青光眼滤过手术抗瘢痕的药物研究进展课件,17,青光眼滤过手术抗瘢痕的药物研究进展课件,18,青光眼滤过手术抗瘢痕的药物研究进展课件,19,青光眼滤过手术抗瘢痕的药物研究进展课件,20,青光眼滤过手术抗瘢痕的药物研究进展课件,21,青光眼滤过手术抗瘢痕的药物研究进展课件,22,青光眼滤过手术抗瘢痕的药物研究进展课件,23,青光眼滤过手术抗瘢痕的药物研究进展课件,24,青光眼滤过手术抗瘢痕的药物研究进展课件,25,青光眼滤过手术抗瘢痕的药物研究进展课件,26,青光眼滤过手术抗瘢痕的药物研究进展课件,27,青光眼滤过手术抗瘢痕的药物研究进展课件,28,青光眼滤过手术抗瘢痕的药物研究进展课件,29,青光眼滤过手术抗瘢痕的药物研究进展课件,30,