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paragonimus1Typical characterFemale genital system:Ovary and womb are at the same level on midline Male genital system:Testes are located at the junction of the posterior fourth of the body2The main parasite including:1.Paragonimus westermani2.Paragonimus skrjabini3.Paragonimus heterotremus3Paragonimus westermani4Oral suckerVetral suckerCecumUterusOvaryTestesExcretory bladder1.adultMorphology562.Egg卵盖卵盖operculum卵壳卵壳eggshell卵卵细胞胞ovotid卵黄卵黄细胞胞yolk cell7Eggoperculumovotidyolk cell8Live cycleAdult eggEggs pass into water in fecesmiracidiumsporocystcercariaAll these stage are growed in the snailleave snail and are eated By crabmetacercariaMan is infective by eating the raw crab.wormWorm move throughThe internal organsadultWorms moving way:Small intestine Abdominal cavityThoracic cavityLungPass the diaphragmatic surfaceAre hatched in the duodenum91011Melania12CrabCrayfish1314Attention:1.Ectopic parasitismSubcutaneous,liver,brain,spinal cord,eye.15Transport host:Some parasite worm invade abnormal host,it can not become adult,it maintain the worm stage,but when it has chance to invade normal host it become adult,the abnormal host called it.16Pathogenesis and clinical manifestation1.Acute period(cause by young worm)The young worms activity cause the partial tissue and organ damaged,bleed,inflamation,the damaged area became a hole and then lead to the tissue ibous,adhesions,particularly the liver.172.Chronic periodA.Pathogenesis in lungThe adults mechanical spoilAnd its secretion and excretion inflammationabscesscystWhen the adult die or move Other place or the content Remove or bsorbedGranulation tissue formedfibrous18Clinical symptomThe patient feel chest discomfort cough,hemoptysis(咳血咳血),Sputum is brown-flake,Egg is often found in the sputum19B.Ectopic parasitismSubcutaneous-cysts in the skinBrain-brain discomfort,epilepsy(癫痫),paralysis(瘫痪)Spinal cord-paresisEye-lose sight or vision disorderPeritoneum(腹膜腹膜)-abdominal pain,diarrhea,blood-stood,enlarging liver2021Lungsymptom 22Brain-spinal cords patient23Peritoneum24Subcutaneous25DiagnosisMake sure whether the patient has the habit of eating the raw crab1.Examination Use the water sedimentation method to find the egg in the fecesUse the direct smear method to find the egg in the sputum262.X-ray,CT for the pleura and brain-spinal cords patient273.Immuniology examinationFor the ectopic parasitismMethod:AST,ELISA,AST-ELISA28EpidemiologyCharcteristic:parasitic zoonosesParagonimiasis infect the wile animal in the nature,when human being come into the area he will be infect.Paragonimiasis had ever taken place in Japan,Korea,Russia29Epidimiology factors:1.Infective source:A.Wild animal:fox,wolf,leopard,cat,dog etc.B.Human being2.Intermediate host:The snail or the crab which grow in the small stream.303.Infective way:A.Eat the raw crab or“drunk crab”B.Eat the raw meat of transport hostC.Drink the unboiling water31Treatment1.Pay attention to the eating habit,not to eat the raw crab,not to drink the unboiling water2.Treat the patient:Praziquantel Albendazole Tribendimidine Artemether Artesunate32Paragonimus skrjabini33Morphology1.AdultShape:OliveSucker:Ventral sucker is larger than oral suckerTestes and ovary have more lobation2.Egg:Similar to paragonimus westermuni34Live cycleEssential similar to paragonimus westermuniThe different from it is that:1.Definitive host:fruit-eating fox(the main)Human:Abnormal host,only young worm infect them.2.The No.1 intermediate host:The snail which grow in the small stream35Tricula spp(拟钉螺）螺）36Pathogenesis and clinical manifestations:Larva migrans:some parasite invade human being,human is not the normal host,it only stay in the stage of young worm,the young worm paraste and migration in the body for a long time,at last it cause particular and peneral pathologic change.37Clinical symptom:1.Subcutaneous type:cystsArea:back and abdomen,four limbs,inguinal region(腹股沟区腹股沟区),head and neck2.Internal organ:differ from what it invade the organ38Diagnosis 1.Operation:2.Blood examination:3.Immunologic testEpidemiology and treatmentSimilar to paragonimus westermuni39
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