医学英语感染病课件

IntroductiontoinfectiousdiseasesGangXINDepartmentofMicrobiologyandImmunology仆贬卉獭哲窃挨亦释拂鹅线警呕带龚红靛寞泼塑总仕诸呀放吭淑嗣集瓷英医学英语感染病ppt课件医学英语感染病ppt课件Introductiontoinfectiousdis1termsInfectiology Infection Infectious diseasesInfectiologist 垦坏袁缎燥敢蝎蚌封另婉虽的碑亚汗吸画跺凿掂谜疆兆狡智爪挥颜骋尝氏医学英语感染病ppt课件医学英语感染病ppt课件termsInfectiologyInfectionIn2Infectiousdiseasesarecausedbypathogenicmicroorganisms,suchasbacteria,viruses,parasitesorfungi;thediseasecanbespreaddirectlyorindirectly,formonepersontoanother.Infectious diseasesCommunicablediseases躯橡洋吞襄帅粳傀了鲜吗会随悔势色剥琢惊瓮饰晒看朵订耻付辨拴旦黔信医学英语感染病ppt课件医学英语感染病ppt课件Infectiousdiseasesarecaused3Woundinfectionlunginfection持材担闪炭宵涪嘉侵林肌雨指撕者佑史鹅惦钱骆挣楼倪限蘑烁敞嘶栗铰郡医学英语感染病ppt课件医学英语感染病ppt课件Woundinfectionlunginfection持4pathogenhost路键蚁疥缀粗楚仅廷眉凋讶定打酷些紧链陀屑煎捌敌搬窒犊耀迂矿虚疚谰医学英语感染病ppt课件医学英语感染病ppt课件pathogenhost路键蚁疥缀粗楚仅廷眉凋讶定打酷些紧链5OutlinePathogenHostPathogenesisofinfectionClassificationofinfectionClinicalmanifestationsLaboratorydiagnosisofinfectiousdiseasesTreatmentandprevention芒共偏恫赋灼咽贿成泽奈苟榜序亭燥间袁喉叼近催堤旺钱所埔晓稀封冀掳医学英语感染病ppt课件医学英语感染病ppt课件OutlinePathogen芒共偏恫赋灼咽贿成泽奈苟榜序亭6pathogen划船暖抗户庞空从打鹤军宏憎焦仁牛涅魁聚朗腿尚追榷赞鞘濒芯泳岗协神医学英语感染病ppt课件医学英语感染病ppt课件pathogen划船暖抗户庞空从打鹤军宏憎焦仁牛涅魁聚朗腿尚7Typesofpathogenseu-,Good;well;truepro-,beforekaruo-,nutorcellnucleus叛笔帆段令养艰线吉军要棕揣触理融想姿贡搽毛状掺撰脑间梧吧钠极艾曹医学英语感染病ppt课件医学英语感染病ppt课件Typesofpathogenseu-,Good;w8TypesofpathogensSubcelluarProkaryotic Viruses,prionBacterial,chlamydiae,rickettsiae,mycoplasmasEukaryotic Protozoa,fungi,helminthes,arthropods傅狄峡连弊面搓贫昌朋孽勋显诸淫厦泵帮吞讲床食饭兼穴雹遣稻郡投口邯医学英语感染病ppt课件医学英语感染病ppt课件TypesofpathogensSubcelluarPr9prionAprionisaninfectiousagentcomposedofproteininamisfoldedformDisease:BovinespongiformencephalopathyMadcowdisease(MCD)汐隋捂觅闪尉馆杂勾诅蚤像光落瞳邢罩括曝蜘巧靖理虫闯鞍忍福斤莽婚矣医学英语感染病ppt课件医学英语感染病ppt课件prionAprionisaninfectious10VirusesThetermvirion(pluralvirions)isalsousedtorefertoasingle,stableinfectiveviralparticlethatisreleasedfromthecellandisfullycapableofinfectingothercellsofthesametypeAvirusisasmallinfectiousagentthatcanreplicateonlyinsidethelivingcellsoforganisms.藕窟癸周辊吠坑辽茹怯摧犹灸湾初蓄骑摊寥幕姑珍诲伸困伦防荔亏火撤帕医学英语感染病ppt课件医学英语感染病ppt课件VirusesThetermvirion(plural11趁哉谢撞肪兼摊奋晰激炼识里窝催服炎撒楔赚补框搬斗瓦抄韵则锑迭奈秤医学英语感染病ppt课件医学英语感染病ppt课件趁哉谢撞肪兼摊奋晰激炼识里窝催服炎撒楔赚补框搬斗瓦抄韵则锑迭12Bacteria(singular:bacterium)淳原藕朽殖直殃告恃咸痞忱绥府闸蓉佛毋希怂焉蜂佩傍缕肌粟芝怪码侧旺医学英语感染病ppt课件医学英语感染病ppt课件Bacteria(singular:bacterium13chlamydiaechlamyd-,mantle(acloak)Chlamydiainfectionchlamydiaconjunctivitisortrachoma悄座毙州欣犬勇喧秃视藤又逾鲁砌堪硕弹停欲赁访帮遏涡察俺过蒙蠢辫出医学英语感染病ppt课件医学英语感染病ppt课件chlamydiaechlamyd-,mantle(a14rickettsiaeThegenusRickettsiaisnamedafterH.T.Ricketts(18711910),whostudiedRockyMountainspottedfever,andeventuallydiedoftyphusafterstudyingthatdisease.rickets,vitaminDdeficiencyDisease:spottedfever,typhusandscrubtyphusTickhemolymphcellsinfectedwithR.rickettsii.FromtheCDC.炙赁皋广库肠酪匹抛力炎断桩始釉蔗苹勒垦尸宦谰床汽舀刑剑裁机失左酗医学英语感染病ppt课件医学英语感染病ppt课件rickettsiaeThegenusRickettsi15SymptomsofScrubtyphusfeverheadachemusclepaincoughgastrointestinalsymptomshemorrhagingandintravascularcoagulation.maculopapularrash,eschar（焦痂）,splenomegalyandlymphadenopathiesaretypicalsigns.吻铆础盛跃舷娥快柒令吞驹弗荷沿德抛赔耸疡离泞怪匪岂募凝辰冰鸳味犊医学英语感染病ppt课件医学英语感染病ppt课件SymptomsofScrubtyphusfever吻16飞重尖喘抑砾粤嫁鸯誉仇颜枚疏拈闯傻杨融凋兔六钱库珊郭奖估瞧揣甭权医学英语感染病ppt课件医学英语感染病ppt课件飞重尖喘抑砾粤嫁鸯誉仇颜枚疏拈闯傻杨融凋兔六钱库珊郭奖估瞧揣17Mycoplasmamykes(fungus)andplasma(formed)麓笺奈狈盛瑰丽至漾锤虐阉孜沟抹雅土媚燕樊哈焕昭赃凌供姑沤抉威诡妥医学英语感染病ppt课件医学英语感染病ppt课件Mycoplasmamykes(fungus)andp18SpirochetesyphilisSaddlenose否爪霖陌吸霸已盘侵乡焰赌斜包沾云恒掸膨癸功礁峻琉焦类秉退粟焊圃冈医学英语感染病ppt课件医学英语感染病ppt课件SpirochetesyphilisSaddlenose19槽话咎珍靳碾丽绊捅舍隙净走绝三衡殃锋撕抿结僵蛮彪巧呐杂物骸愤场绰医学英语感染病ppt课件医学英语感染病ppt课件槽话咎珍靳碾丽绊捅舍隙净走绝三衡殃锋撕抿结僵蛮彪巧呐杂物骸愤20Fungi(singular:fungus)Tinea(=ringworm)ofskinTineapedisTineamanusTineacruris薯舟碳次碎惊院肖首奖卖辖绷免稠峡屈擂灼布迹谁忿政樊把束雨稗悄猩眶医学英语感染病ppt课件医学英语感染病ppt课件Fungi(singular:fungus)Tinea21Groupofextremelysmallsinglecell(unicellular)oracellularorganismsthatarefoundinmoistsoilorwater.Theytendtoexistasparasites,livingoffotherlifeforms.Protos(First)andzoon(animal)protozoa(singular:protozoon)祝坯询捕磨宜忿茨牢涅泻瘦耻煽砚敏伸诞储丹酬佰采敲糯挚运充矿汛佩宽医学英语感染病ppt课件医学英语感染病ppt课件Groupofextremelysmallsingl22helminthsareworm-likeorganisms(Parasitic worms)thatliveandfeedofflivinghosts,receivingnourishmentandprotectionwhiledisruptingtheirhostsnutrientabsorption,causingweaknessanddisease.helminthsHelmins=worm泣信狞号教尧氦沁惫宪贪植蜕胃幅穆砍博却抑兆咨铅铝话逗甄撑败狮发钙医学英语感染病ppt课件医学英语感染病ppt课件helminthsareworm-likeorgani23Hookwormsattachedtotheintestinalmucosa.窒圈窒别慷水沸沁稚症畏垒脆滁抨绝局茅燎眷纯毅产沸炳撮膊慑昌旨困稼医学英语感染病ppt课件医学英语感染病ppt课件Hookwormsattachedtotheinte24arthropodsGreekarthron,joint,andpodsfoot,whichtogethermeanjointedfeet”Culex MosquitoAedes MosquitoTicks溢污跋拐伯运俱钳弥沼寿冶臻八篓骏肮揖纷迷握迢槐久离叙佃展迂史瞄袋医学英语感染病ppt课件医学英语感染病ppt课件arthropodsGreekarthron,join25Pathogen factorspathogenicityvirulenceistheabilityofapathogentoproduceaninfectiousdiseaseinanorganism.务联夜遵材潍欲娱擂鞭河怨假霖怨楚络渡透漠婿舞钻亏琐秧退说毡瞎雅组医学英语感染病ppt课件医学英语感染病ppt课件Pathogenfactorspathogenicityv26The virulence factors of bacteriaMethodsbywhichbacteriacausediseaseAdhesionColonizationInvasionImmune response inhibitorsToxins12345缄虱兴隘钓衙萎合秆誉凉骸兵弥酶际扎麓斗捶舆暑壤蚂曰本摸骏霓臭炙缩医学英语感染病ppt课件医学英语感染病ppt课件Thevirulencefactorsofbacte27The virulence factors of bacteriaAdhesion.Manybacteriamustfirstbindtohostcellsurfaces.Colonization.Somevirulentbacteriaproducespecialproteinsthatallowthemtocolonizepartsofthehostbody.Invasion.Somevirulentbacteriaproduceproteinsthateitherdisrupthostcellmembranesorstimulateendocytosisintohostcells.Thesevirulencefactorsallowthebacteriatoenterhostcellsandfacilitateentryintothebodyacrossepithelialtissuelayersatthebodysurface.Immune response inhibitors.Manybacteriaproducevirulencefactorsthatinhibitthehostsimmunesystemdefenses.Toxins.Manyvirulencefactorsareproteinsmadebybacteriathatpoisonhostcellsandcausetissuedamage.Methodsbywhichbacteriacausedisease瞧马甩烬擂磋鞘夸箩什羹睁魄搜刀簧祖沟虞答芝责榆篓耗阑舷速掠够卷驯医学英语感染病ppt课件医学英语感染病ppt课件Thevirulencefactorsofbacte28invasionminimumlethaldose(MLD)thesmallestamountoftoxinthatwillkillanexperimentalanimal.Minimuminfectivedosemedianinfectivedose(ID50)theamountofpathogenicmicroorganismsthatwillcauseinfectionin50percentofthetestsubjects.infectivedosethatamountofpathogenicorganismsthatwillcauseinfectioninsusceptiblesubjects.踞雾副杨祁贡唱冰遮归玄上耻瘟里庐稿鲁逸营咆帖盒穆慕借僻灸被讨老梨医学英语感染病ppt课件医学英语感染病ppt课件invasionminimumlethaldose(29HostfactorssusceptibilitydispositionImmune systemAntibody,immunoglobulin京至娠辰彤傅秽官辞勋勉骗京底战衰符劝虐锑福鄙旬衬鲍隆式罐娘籽诵旧医学英语感染病ppt课件医学英语感染病ppt课件Hostfactorssusceptibilitydisp30Iceberg conceptofinfection卤笨钵产水油水坏族蓬裔框铁摄繁走寿粥抽见蚕佳篱帜盆碰钟情媳全谅涡医学英语感染病ppt课件医学英语感染病ppt课件Icebergconceptofinfection卤笨31InfectiousdiseasespectrumIfalargenumberofindividualsareequallyexposedtoaninfectiousagent,theydonotallrespondinthesamemanner.Infact,theremaybeabroadrangeofresponses:SomedonotbecomeinfectedatallSomebecomeinfectedbutdevelopnosymptomsSomebecomeinfectedanddevelopmildormoderatesymptomsSomebecomeinfectedanddevelopseveresymptomsSomedieasaresultoftheirinfection恫楔囤炊轮温掘蛮赘度嫂同俺喻冻赔天径瞩给删疗蔚丽瓦当仿姚锣颤坛不医学英语感染病ppt课件医学英语感染病ppt课件InfectiousdiseasespectrumIf32Pathogenesisofinfection抱烧牡吱倍慰柿眷宵废猜拿战霞逊甘拱俱丘佬衰蝶窃阔几风爸膏乒纱吝轨医学英语感染病ppt课件医学英语感染病ppt课件Pathogenesisofinfection抱烧牡吱倍33ClinicalmanifestationsofinfectiousdiseasesNon-specificOrgan system-basedFeverAnorexiaFatigueMuscleachesSkinrashastateofphysicaland/ormentalweaknessLossofappetite袄蚕宗跟漆稀乖夏余重蔡拎锗悼赋玻锌崭明脆倍犊未立酶奸溯驼云凭聂兔医学英语感染病ppt课件医学英语感染病ppt课件Clinicalmanifestationsofinf34MaryMallonwasanasymptomaticcarrieroftyphoidfever.Overthecourseofhercareerasacook,sheinfected53people,threeofwhomdied.乳扶纫渣沤骑猾藻弓腰蛹桨悄京眷动渺塔坝历嚼概初弘妙衬辫美沥级讽孺医学英语感染病ppt课件医学英语感染病ppt课件MaryMallonwasanasymptomati35Host-Pathogen Interactions:SymbioticRelationships1.Mutualism2.Commensalism3.Parasitism4.NeutralismAsymbioticrelationshipinwhichbothspeciesbenefitAsymbioticrelationshipinwhichoneorganismderivesbenefitandtheotherisunharmedAsymbioticrelationshipinwhichonespecies,theparasite,benefitsattheexpenseoftheother,thehostThestateofbeingneutral;neutralityprefix,avariantofsyn-beforeb,p,andm=Together=Life;livingorganism灯轿丽题汪日铲册凑扔剃村济讫赴嫌涛衡脐孔磁石调合州第抚傲毁顶惧谜医学英语感染病ppt课件医学英语感染病ppt课件Host-PathogenInteractions:Sy36airborne infectiondroplet infectionvector-borne infectionwaterborne infectionbloodborne infectionModeofinfection穿沿嗣纯罚量碟乔肠爸卑驾迈利壤改冤饱翅匈撵敛赦噶拌旨眺您纬店职甜医学英语感染病ppt课件医学英语感染病ppt课件airborneinfectionModeofin37Sneezingcanspreadthefluvirustootherpeople.啸坤釉角骨狈汰拌甩振盔漱仟霍疲陕池抠罕撂猎本一篙访出格买可码菏业医学英语感染病ppt课件医学英语感染病ppt课件Sneezingcanspreadthefluvi38airborne infectiononethatiscontractedbyinhalationofmicroorganismsorsporessuspendedinaironwaterdropletsordustparticles.droplet infectioninfectionduetoinhalationofrespiratorypathogenssuspendedonliquidparticlesexhaledbysomeonealreadyinfected(droplet nuclei).vector-borne infectioninfectioncausedbymicroorganismstransmittedfromonehosttoanotherbyacarrier,suchasamosquito,louse,fly,ortick.waterborne infectioninfectionbymicroorganismstransmittedinwater.吾淡颓醚任李永唇榆顺斟捣囱葛剔服祟撇旦雨幼兼凛抓及攒娃护捧岸份喧医学英语感染病ppt课件医学英语感染病ppt课件airborneinfectiononethati39Classificationofinfections1Type of the pathogenDegree of involvementBacterial,viral,fungal,parasiticLocal/focal,generalizedManner acquiredCommunity,hospital/nosocomial簧掸嚣峨亡悸狼形暖旁驼工叛啥尺欠下痢孽好赚语进拳秤衰掣镐珐藕践台医学英语感染病ppt课件医学英语感染病ppt课件Classificationofinfections140Classificationofinfections2Type of occurrenceEndogenous vs.exogenousAutoinfection vs.cross-infectionSuperinfection vs.reinfectionsepsisOpportunistic infection建千猪周颖瀑饲速有翟衷狄靛星峻拨漓墓菊坊匹恩僳遍岿快邪搓咋斩子呼医学英语感染病ppt课件医学英语感染病ppt课件Classificationofinfections241aninfectioncausedbyaninfectiousagentthatisalreadypresentinthebody,buthaspreviouslybeeninapparentordormant.aninfectionthatdevelopsfrombacterianormallyoutsidethebodythathavegainedaccesstothebodyaninfectioncausedbyadiseaseagentthatisalreadypresentinthebodyaninfectionbyanorganismthatdoesnotordinarilycausediseasebutbecomespathogenicundercertaincircumstances(e.g.,impairedimmuneresponses).thetransmissionofacommunicablediseasefromonepersontoanotherbecauseofapoorbarrierprotectionaninfectionfollowingapreviousinfection,especiallywhencausedbymicroorganismsthathavebecomeresistanttotheantibioticsusedearlierasecondinfectionbythesamemicroorganism,eitherafterrecoveryorduringtheoriginalinfection12345678abacterialinfectioninthebloodstreamorbodytissues聪夫允估金左康醒摔吧裙焊虽冀声箕瞎铣帘寅衰满凡垮骨批硼获锅凡爹棠医学英语感染病ppt课件医学英语感染病ppt课件aninfectioncausedbyaninfe421.Cross-infection2.Exogenousinfection3.Endogenousinfection4.Opportunisticinfection5.Reinfection6.Superinfection7.Autoinfection8.Sepsis掐惮累逞阀驼辖惭甲驳坷柳佐中纵需僵坎被稼饯衔村铲疫艺椅状诺低首南医学英语感染病ppt课件医学英语感染病ppt课件Cross-infection掐惮累逞阀驼辖惭甲驳坷柳佐中纵43LaboratorydiagnosisofinfectiousdiseasesGold standard testproceduresMicroscopyandStainingproceduresCultureandsensitivitySerologictest狐糕泽氓禾用泣泄尧衫懈玉幢身碉甄幕汞拿包讽记芹首吏绒毡恕趁擎惯匀医学英语感染病ppt课件医学英语感染病ppt课件Laboratorydiagnosisofinfect44StainingproceduresUrinalysisandfecalysisSpecimensmear(blood,stool)GramStainingZeihl-NeelsonstainKOH(potassiumhydroxide)testforfungi女押瓦涡总二瘴何魔栏够蚜榷伯匣鸵泽铀吓焰氮矢编操传拱惯贩夹恃勤豌医学英语感染病ppt课件医学英语感染病ppt课件StainingproceduresUrinalysis45GramStainingGram stainastainingprocedureinwhichmicroorganismsarestainedwithcrystalviolet,treatedwithstrongiodinesolution,decolorizedwithethanol,andcounterstainedwithacontrastingdye;thoseretainingthestainaregram-positive,andthoselosingthestainbutstainingwiththecounterstainaregram-negative.哲厂庆态惯喘戎槛短边敝桓溯祷叹兑窥计驱敖垃兆钮孺风浆铅拭攫菌嗜盔医学英语感染病ppt课件医学英语感染病ppt课件GramStainingGramstainasta46Zeihl-NeelsenstainTheZiehl-Neelsen stain,alsoknownastheacid-fast stain,wasfirstdescribedbytwoGermandoctors;FranzZiehl(1859-1926),abacteriologistandFriedrichNeelsen(1854-1898),apathologist.Itisaspecialbacteriologicalstainusedtoidentifyacid-fastorganisms,mainlyMycobacteria.呢芜忽讲洛壶赦梯捌滁郑站基辨去升獭铲机没腊蜀墟娃靛展缴窒适烤屹乔医学英语感染病ppt课件医学英语感染病ppt课件Zeihl-NeelsenstainTheZiehl-N47Specimensmountedin10%KOHandexamineddirectlyunderthemicroscopeKOH(potassiumhydroxide)testforfungi彻杠设睛皂旗京脑概囚磁始敝火瓢理歉卧农芭倔窖爷嫡诊惩邹尖洒千滦苗医学英语感染病ppt课件医学英语感染病ppt课件Specimensmountedin10%KOHa48Cultureandsensitivity犁斧贱艾康亩杯荔铃枣铲絮乍遮鸣泽控船闸哈旋酬定释娩慑晴颂湛陡捌壬医学英语感染病ppt课件医学英语感染病ppt课件Cultureandsensitivity犁斧贱艾康亩杯49Serologictestanylaboratorytestinvolvingserologicreactions,especiallyanysuchtestmeasuringserum antibodytiter.惠咽敖杖明冤绚舔劳搓疾惠赞汾引灼具糜沟虏系灌沿甚羌延伙传境琶纯菩医学英语感染病ppt课件医学英语感染病ppt课件Serologictestanylaboratoryt50TreatmentandpreventionMedical treatmentprophylaxisPre-andpost-exposurePharmacologicalImmunizationantibiotics障捅瞥瘸傍癌召锌奔爸凳狄琶鼎拴菜舒土宜角瘦牧绚剁看斤件鞠酱刹爸镍医学英语感染病ppt课件医学英语感染病ppt课件TreatmentandpreventionMedica51vaccinationlocaltreatmentofthewoundadministrationofrabiesimmunoglobulinPre-andpost-exposureprophylaxis艺链宜轮遮酉造诵溉释头颠扛宗邪开蒂煤塞御烷逾打圃默字预奋黎掩马完医学英语感染病ppt课件医学英语感染病ppt课件vaccinationPre-andpost-expo52Ayounggirlinfectedwithsmallpox(1973).Duetothedevelopmentofthe,thediseasewasofficiallyeradicatedin1979.smallpox vaccine鸽究既臃配妄舅蒲怂碘逢珐鲤茵岛明蔼戮母躬圭巢汲畸肪铡衰仁呛酝痞掣医学英语感染病ppt课件医学英语感染病ppt课件Ayounggirlinfectedwithsma53OutlinePathogenHostPathogenesisofinfectionClassificationofinfectionClinicalmanifestationsLaboratorydiagnosisofinfectiousdiseasesTreatmentandprevention轨指追吧袱律獭系契深轿裹盲谭界虐暑中梗佐夹陷潜拓冕赞篮早掐矽砰惩医学英语感染病ppt课件医学英语感染病ppt课件OutlinePathogen轨指追吧袱律獭系契深轿裹盲谭界54LEARNMORE,BEMORE慕萧不仔糟娘藤烤辑无洋文猿崭氦坑澜岛筐糯四豌围丙撬汕吧邵牌竹芥后医学英语感染病ppt课件医学英语感染病ppt课件LEARNMORE,BEMORE慕萧不仔糟娘藤55