组织胚胎学 ppt课件

组织胚胎学课件组织胚胎学课件中国医科大学中国医科大学基础医学院基础医学院组胚组胚英文教学组英文教学组1 业精于勤荒于嬉 行成于思毁于随 【医学生物PPT，欢迎收藏分享】豆丁网友 组织胚胎学课件中国医科大学1业精于勤荒于嬉行成于思毁HUMANEMBRYOLOGYDepartmentofHistologyandEmbryologyDepartmentofHistologyandEmbryologyChinaMedicalUniversityChinaMedicalUniversityHUMANChapter4Chapter4FurtherDevelopmentofEmbryoFurtherDevelopmentofEmbryo Chapter4Formation and differentiation of trilaminar germ discFormationanddifferentiation1.formationof1.formationofepiblastepiblastandandhypoblasthypoblast:ByBy thethe 8th8th day,day,thethe innerinner cellcell massmassdifferentiatesintotwolayersofcellsdifferentiatesintotwolayersofcellsepiblast(columnar)hypoblast(cuboidal)bilaminargermdisc1.formationofepiblastandAmnionic cavityepiblasthypoblastBilaminargerm discAmnionicepiblasthypoblastBila-epiblastepiblast:primaryectoderm:primaryectodermamnioticcavity:amnioticfluidamnioticcavity:amnioticfluidroof:amniogeniccellsroof:amniogeniccellsfloor:epiblastfloor:epiblast-epiblast:primaryectoderm-hypoblasthypoblast:primaryendoderm:primaryendoderm hypoblasthypoblastHeusersHeusersmembranemembraneprimaryyolksacprimaryyolksac-hypoblast:primaryendoderAmnionic cavityepiblasthypoblastBilaminargerm discExtra-embryonic mesodermPrimary yolk sacAmnioniccavityepiblasthypoblBody stalkExtra-embryoniccavityExtra-embryonic mesodermPrimary yolk sacsecondary yolk sacBodystalkExtra-embryonicExtra extra-embryonicmesodermextra-embryonicmesodermextra-embryoniccavity(chorioniccavity)extra-embryoniccavity(chorioniccavity)-viscerallayer-viscerallayer-parietallayer-parietallayer/secondaryyolksac:yolksac/secondaryyolksac:yolksac-body-body stalkstalk(connecting(connecting stalk):stalk):formedformedbyextra-embryonicmesodermbyextra-embryonicmesodermextra-embryonicmesoderm2.2.formationofmesoderm:formationofmesoderm:intheearlyofthe3rdweekintheearlyofthe3rdweek-primitiveprimitivestreakstreak:cellscellsofofepiblastepiblast proliferateproliferatetotoformformaalongitudinallongitudinalarrangedarrangedcellcordcellcord*determinationofheadandtailofgermdisc*determinationofheadandtailofgermdisc2.formationofmesoderm:2.2.formationformation ofof mesoderm:mesoderm:inin thetheearlyofthe3rdweekearlyofthe3rdweek-primitivestreakprimitivestreak-primitivenodeprimitivenode(primitiveknotprimitiveknot)2.formationofmesoderm:int2.2.formationformation ofof mesoderm:mesoderm:inin thetheearlyofthe3rdweekearlyofthe3rdweek-primitivestreakprimitivestreak:-primitivenodeprimitivenode(primitiveknotprimitiveknot)-primitivepitprimitivepit(blastoporeblastopore)2.formationofmesoderm:int组织胚胎学ppt课件-mesodermmesoderm:intra-embryonicmesoderm:intra-embryonicmesoderm-endodermendoderm:hypoblasthypoblast cellscells areare replacedreplaced bybyepiblastcellsepiblastcells-ectodermectoderm:epiblastepiblast changedchanged thethe namename intointoectodermectoderm-mesoderm:intra-embryonicmbytheendofthe3rdweekbytheendofthe3rdweektrilaminargermdisctrilaminargermdisc:endoderm+mesoderm+ectodermendoderm+mesoderm+ectodermbytheendofthe3rdweek-headprocessnotochordaltube-headprocessnotochordaltubenotochordnotochord-buccopharyngealmembranebuccopharyngealmembrane-cloacalmembrane-cloacalmembranenotochord-headprocessnotochordaltu3.3.differentiationdifferentiation ofof trilaminartrilaminar germgerm discdisc 4 4thth88ththweeksweeks-differentiationdifferentiation:samesamecellscellswhichwhichareareprimordialprimordial andand inmutureinmuture differentiatedifferentiate intointodifferentdifferentcellscellswhichwhichhavehavespecificspecificstructurestructureandfunctionandfunction-induction-induction:somesometissuestissueseffecteffectthethedifferentiation,differentiation,andanddeterminedeterminethethedifferentiatingorientationofanothertissuedifferentiatingorientationofanothertissue3.differentiationoftrilamina(1)(1)differentiationofectodermdifferentiationofectoderm:from18from18thth1919ththdaysdays-neuralneural plateplate:neuro-epitheliumneuro-epithelium(neural(neuralectoderm):pseudostratifiedcolumnarepi.ectoderm):pseudostratifiedcolumnarepi.neuralplateNotochord(1)differentiationofectoder(1)(1)differentiationofectodermdifferentiationofectoderm:from18from18thth1919ththdaysdays-neuralplateneuralplate-neuralgrooveneuralgroove-neuralfoldneuralfoldNeural grooveNotochord(1)differentiationofectoderNeural tubeAnterior and posterior neuropores-neural tube:CNS /anterior neuropore:closed by 25th days /posterior neuropore:closed by 27th daysNeuraltubeAnteriorandposteranencephalySpinabifidaanencephalySpinabifida-neuraltube:CNS-neuralcrest:twolinesofcellcordsganglions-neuraltube:CNS(2)differentiationofmesoderm(2)differentiationofmesoderm:17:17ththdaydayNeural grooveIntermediatemesodermLateral mesoderm paraxialMesoderm endoderm(2)differentiationofmesoderm-paraxialmesoderm-paraxialmesoderm somite:somite:2020thth days,days,3 3pairs/perpairs/perday,day,42-4442-44pairsbytheendof5pairsbytheendof5ththweeksweeks-sclerotome:bone,cartilage-sclerotome:bone,cartilage-dermatome:-dermatome:dermisandhypodermisdermisandhypodermis-myotome:skeletalmuscle-myotome:skeletalmuscle-paraxialmesodermIntermediatemesodermNeural canalSomite endodermIntraembryonic cavityIntermediateNeuralcanalSomite-intermediatemesoderm:intermediatemesoderm:kidneyandreproductivesystemkidneyandreproductivesystem-intermediatemesoderm:-lateralmesodermlateralmesoderm:Intra-embryoniccoelomIntra-embryoniccoelom:bodycavity:bodycavityparietalparietalororsomaticsomaticmesodermmesoderm:muscle,muscle,CT,CT,parietalparietallayerofpleura,peritoneumandpericardiumlayerofpleura,peritoneumandpericardiumvisceralvisceral oror splanchnicsplanchnic mesodermmesoderm:muscle,muscle,CTCT ofofdigestivedigestivetract,tract,visceralviscerallayerlayerofof pleura,pleura,peritoneumperitoneumandpericardiumandpericardium-lateralmesoderm:Parietal mesodermvisceralmesodermIntra-embryoniccavityParietalvisceralIntra-embryon3.3.differentiationofendodermdifferentiationofendoderm:primitivegutprimitivegut:digestive,:digestive,respiratoryandurinarysystemrespiratoryandurinarysystem foregutmidguthindgutCloacal membraneoropharyngeal membrane3.differentiationofendoderm组织胚胎学ppt课件1.Embryonicperiodis1.Embryonicperiodis A.fromfertilizationtotheendofweek2A.fromfertilizationtotheendofweek2B.fromfertilizationtotheendofweek8B.fromfertilizationtotheendofweek8C.fromweek3totheendofweek8C.fromweek3totheendofweek8D.fromweek5totheendofweek8D.fromweek5totheendofweek8E.fromweek9untilbirthE.fromweek9untilbirth2.Howlongwillanindividualstayintheuterusofits2.Howlongwillanindividualstayintheuterusofitsmother?mother?A.18weeksA.18weeksB.28weeksB.28weeksC.38weeksC.38weeksD.48weeksD.48weeks E.58weeksE.58weeksB BC C1.EmbryonicperiodisBC3.Whatispenetratedbyaspermatozoonduringthe3.Whatispenetratedbyaspermatozoonduringtheprocessoffertilizationprocessoffertilization A.oogoniumA.oogoniumB.primaryoocyteB.primaryoocyteC.secondaryoocyteC.secondaryoocyteD.primaryfollicleD.primaryfollicleE.primordialfollicleE.primordialfollicle4.Whichproteinisreceptorofspermatozoaonthezona4.Whichproteinisreceptorofspermatozoaonthezonapellucida?pellucida?A.ZP1A.ZP1 B.ZP2B.ZP2C.ZP3C.ZP3D.ZP4D.ZP4 E.ZP5E.ZP5C C C C3.Whatispenetratedbyaspe5.Thetimeofimplantationis5.Thetimeofimplantationis A.from1st-2nddayto7th-8thdayA.from1st-2nddayto7th-8thdayB.from3rd-4thdayto9th-10thdayB.from3rd-4thdayto9th-10thdayC.from5th-6thdayto11th-12thdayC.from5th-6thdayto11th-12thdayD.from7th-8thdayto13th-14thdayD.from7th-8thdayto13th-14thdayE.from9th-10thdayto15th-16thdayE.from9th-10thdayto15th-16thday6.Whichstructureisnotbelongtoearlyblastocyst?6.Whichstructureisnotbelongtoearlyblastocyst?A.trophoblastA.trophoblastB.zonapellucidaB.zonapellucidaC.innercellmassC.innercellmassD.blastocoeleD.blastocoele E.endodermE.endodermC C E E 5.Thetimeofimplantationis7.Whichisnotcorrectaboutimplantation7.Whichisnotcorrectaboutimplantation A.blastocystwillbeimbeddedintheendomytriumA.blastocystwillbeimbeddedintheendomytriumB.zonapellucidadisappearsB.zonapellucidadisappearsC.polartrophoblastsecretesproteinaseC.polartrophoblastsecretesproteinaseD.endomytriumisinproliferativephaseD.endomytriumisinproliferativephaseE.thereisacorpusluteumofpregnancyintheovaryE.thereisacorpusluteumofpregnancyintheovary8.Themostcommonpositionofimplantationis8.ThemostcommonpositionofimplantationisA.mucusofuterinetubeA.mucusofuterinetubeB.mucusofampullaryportionofuterinetubeB.mucusofampullaryportionofuterinetubeC.ovaryC.ovaryD.mucusofcervixofuteruD.mucusofcervixofuteru E.mucusofbodyofuterusE.mucusofbodyofuterusD D E E 7.WhichisnotcorrectaboutQuestions1.1.DescribetheformationofbilaminargermdiscanditsDescribetheformationofbilaminargermdiscanditsassociatedstructures.associatedstructures.2.2.DescribetheformationofDescribetheformationoftrilaminartrilaminargermdiscanditsgermdiscanditsassociatedstructures.associatedstructures.3.3.Describethedifferentiationofthreegermlayersbriefly.Describethedifferentiationofthreegermlayersbriefly.4.Previewfetalmembraneandplacenta.4.Previewfetalmembraneandplacenta.Chapter4Chapter4Chapter4FurtherDevelopmentofEmbryoFurtherDevelopmentofEmbryoFurtherDevelopmentofEmbryo Questions1.Describetheforma