神经病理性疼痛诊疗专家共识解读课件

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,神经病理性疼痛(Neuropathic Pain,NeP)诊疗专家共识解读,目录,NeP的简介,NeP的病因和发病机制,3|NeP的临床表现,4,NeP的诊断,5NeP的治疗,目录,1NeP的简介,2|NeP的病因和发病机制,3NeP的临床表现,4NeP的诊断,5NeP的治疗,神经病理性疼痛的定义,Neu,由躯体感觉系统的损害或疾病导致的疼痛,SIG,(Neuropathic pain is defined as pain caused by a lesion or,disease of the somatosensory system),2019年,Vg:IASp,由神经系统的原发损害或功能障碍,所引发或导致的疼痛,International Association for the Study of Pain,Pain initiated or caused by a primary lesion or,1994年,dysfunction in the nervous system,NeuPSIG:ASP神经病理性疼瘤特别兴趣小组,AsP:国际疼痛学会,Jensen TS,Baron R,Haanpaa M,et al.Pain.2019:152(10):2204-5,神经病理性疼痛分为周围性和中枢性两种,周围性神经病理性疼痛,中枢性神经病理性疼痛,带状疱疹后神经寫,脑卒中后疼痛,糖尿病性周神经病变,空洞正疼痛,缺血性脊髓病疼痛,压性脊病(如肴髓斗颈椎病、肿瘤)疼痛,根性神经病变(颈、胸或H,放射后肴病疼痛,嵌压性神经病变如腕管综合征等),损伤性疼痛,发性硬化相关性疼痛,帕金森病性疼痛,化疗后神经病变,肢痛,放疗后神经病变,炎疼痛,残肢痛,西精性多发神经病变,梅毒性神经病变,毒物接触性神经病变,免疫性神经病变,1.DworkinRH.BackonjaM.Rowbotham MC.et al.Arch Neurol.2019 60(11):1524-34,神经病理性疼痛患耆数量众多,NeuPSIG,NeP患病率约为33%8.2%,欧洲研究资料,NeP患病率高达80%2,目前我国神经病理性疼痛患者约有9000万,NeuPSIG:IASP神经病理性疼痛特别兴趣小组,R,Tolle.European Journal of Pain Supplements,2019(4):161-165,神经病理性疼痛患者常伴随焦虑和睡眠障碍,疼痛,恶性循环导致,患者生活质量,焦虑症或抑,郁症,睡眠障碍,1.Raymond L Rosales,et al.School of Neuropathic Pain:A Practical Guide For Clinicians In The Management Of Neuropathic Pain.2019.12,NeP患者常伴随其他不适症状,睡眠障碍,无力,困倦,认知功能障碍,抑郁,33,焦虑,食欲不振,80,相关症状导致不适的患者比例(%,1.Raymond L Rosales,et al.School of Neuropathic Pain:A Practical Guide For Clinicians In The Management Of Neuropathic Pain.2019.12,神经病理性疼痛患耆生活质量远低于一般人群,般人群(n=8930)一研究人群(n=136),躯区体功能生理职能躯体疼痛健康状况活力社会功能情绪职能心理,*sF-36健康调查量表:评估8种健康状况,分数越高状态越好,1.Meyer-Rosberg K,et al.Eur J Pain 2019(5)4 391-403,目录,NeP的简介,2|NeP的病因和发病机制,3NeP的临床表现,4NeP的诊断,5NeP的治疗,