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,单击此处编辑母版标题样式,*,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,D-dimer in Pulmonary embolism,The 1st Hospital Of Jilin University,Zhenggiu Wang,D-dimer in Pulmonary embolismT,1,Outline,D-dimer assays Methods,D-dimer cut-off and Age,D-dimer and Clinical Probability,D-dimer and anticoagulation,D-dimer in Other diseases,Formation of D-dimer,OutlineD-dimer assays Methods,2,Part I,Formation of D-dimer,Part I,3,D-二聚体在肺栓塞中的应用-英文ppt课件,4,D-二聚体在肺栓塞中的应用-英文ppt课件,5,Part II,D-dimer Methods,Part II,6,Sensitivity and specificity of different D-dimer assays,Role of D-dimer in VTE;Imaging Decisions 3/2007,D-dimer Methods,Sensitivity and specificity o,7,Part III,D-dimer and Clinical Probability in Suspected PE,8,D-dimer and Clinical Probability in Suspected PE,Acute Pulmonary Embolism；Curr Probl Cardiol 2010;35:314-376.,D-dimer and Clinical Probabili,9,Arch Intern Med.2004;164:2483-2487,D-dimer and Clinical Probability in Suspected PE,Arch Intern Med.2004;164:2483-,10,The cut-off of D-dimer in VTE,Arch Intern Med.2004;164:2483-2487,D-dimer and Clinical Probability in Suspected PE,The cut-off of D-dimer in VTE,11,Part IV,D-dimer and anticoagulation,Part IV,12,D-dimer concentration and anticoagulant therapy,NEJM2006;355;1780-9;D-dimer Testing to Determine the Duration,of Anticoagulation Therapy,曲线1,曲线2,曲线3,D-dimer concentration and an,13,Part IV,D-dimer and anticoagulation,Baseline characteristics：年纪更大、并发症更多、随访时间更长,Part IV Baseline character,14,Part IV,D-dimer and anticoagulation,Figure 3.Cumulative incidence and hazard ratios(HRs)of main outcomes according to D-d time course from the third month(T90)to the 13th month(T390).,Group 1:Patients in whom D-d was normal at T90 and afterward (with D-d becoming abnormal only once).,Group 2:Patients in whom D-d became abnormal at T90 and afterward remained altered persistently or at least twice.,Group 3:Patients in whom D-d became abnormal after T90 and afterward remained abnormal persistently or at least twice.,Part IV Figure 3.Cumula,15,NEJM,356;4;January 2007;D-dimer and anticoagulation,NEJM,356;4;January 2007;D-dim,16,The cut-off of D-dimer in VTE,D-dimer and recurrent VTE,The cut-off of D-dimer in VTE,17,Part II,D-dimer and Age,D-dimer and recurrent VTE,Part II D-dimer and,18,D-dimer and recurrent VTE,D-dimer and recurrent VTE,19,Part V,D-dimer cut-off and Age,Part V,20,D-dimer in Pulmonary embolism,The 1st Hospital Of Jilin University,Acute Pulmonary Embolism；Curr Probl Cardiol 2010;35:314-376.,D-dimer in Pulmonary embolismT,21,Acute Pulmonary Embolism；Curr Probl Cardiol 2010;35:314-376.,Fatal PE according to Age,Acute Pulmonary Embolism；Curr,22,Figure 1:Distribution of D-dimer results for age groups,(a)80years.A D-dimer result is reported as negative if below 500ng/ml,showed by bold ventical line.,D-dimer assay in the elderly,Internal Medicine Journal 37(2007)607-613,D-dimer and Age,Figure 1:Distribution of D-dim,23,D-dimer and Age,D-dimer and Age,24,D-dimer and Age,D-dimer and Age,25,D-dimer and Age,D-dimer and Age,26,Part VI,D-dimer in other diseases,Part VI,27,Part V,D-dimer in Caner,Acute Pulmonary Embolism；Curr Probl Cardiol 2010;35:314-376.,D-dimer and cancer,Part V Acute P,28,D-dimer and F1+2 levels in Different sites of cancer,D-dimer and F1+2 levels in Dif,29,The cut-off of D-dimer in VTE,Elevated D-dimer+(F1+2),Elevated(F1+2),Elevated D-dimer,Nonelevated D-dimer+(F1+2),D-dimer and cancer,The cut-off of D-dimer in VTE,30,Part VI,D-dimer in other diseases,D-dimer for Acute Aortic Dissection,Part VI D-d,31,Thank You!,Thank You!,32,
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