代谢综合征的因子分析

*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,*,*,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,代谢综合征的因子分析,背景：代谢综合征MS存在较多争议,是否存在，定义，病理生理机制等,目的：用因子分析的方法分析MS各组分在不,同人群NGT,IGT,DM和CHD的聚,集情况,2,因子分析的根本原理与适用研究范围,1904年Chales Spearman 心理学领域,体育、教育、心理与经济等领域,近年在代谢综合征MS领域也有应用,将多个实测变量转换成少数几 “因子,3,因子分析应用举例,100,名学生各科考试成绩如下：,4,因子分析应用举例,因子,1,(,语言表达能力,),因子,2,(,逻辑思维能力,),数学,-0.387,0.790,物理,-0.172,0.841,化学,-0.184,0.817,语文,0.879,0.343,历史,0.911,0.210,英语,0.913,0.216,5,对象,方法,结果,讨论,6,研究对象,糖尿病病史的患者,TG10mmol/L,数据有缺失,CHD,组,NGT,组,IGT,组,新诊断,DM,组,去除,1090,人,入选对象,1254,人,平均年龄,60.49,岁,男,570,人，女,684,人,2004,年,6,月至,8,月,北京石景山地区,40,岁,（平均年龄,61,岁）,流行病学调查人群，,共计,2344,人,无,DM,病史者,行,75gOGTT,测量,FBG,、,2hBG,FINS,、,2hINS,、,TG,、,HDL,、,WC,、,BMI,7,研究对象特点,8,对象,方法,结果,讨论,9,研究方法,培训合格人员,统一测量,体质测量,血压,生化指标,WC,BMI,SBP,DBP,FBG,FINS,PBG,PINS,TG,HDL-C,SAS,软件,EFA,10,对象,方法,结果,讨论,11,NGT,组,变量,因子,1,因子,2,因子,3,因子,4,FINS,0.47463,0.50406,-0.03534,-0.33922,PINS,0.06157,0.81385,0.02423,-0.25946,BMI,0.87355,0.06232,0.13458,-0.17114,WC,0.87462,0.08205,0.22071,-0.16651,SBP,0.19565,0.14093,0.87211,-0.03310,DBP,0.09560,0.03765,0.88247,-0.16616,TG,0.13168,0.21239,0.16357,-0.69793,HDL,-0.26611,-0.01808,-0.08127,0.69679,FBG,0.36478,0.40208,0.07266,0.42109,PBG,0.03462,0.77241,0.15871,0.07128,方差贡献率,0.3295,0.1343,0.1206,0.1030,累计方差,0.3295,0.4638,0.5844,0.6874,12,研究结果,SBP,DBP,BMI,、,WC,PINS,FBG,PBG,FINS,TG,HDL,4,1,2,3,NGT,组,13,IGT,组,变量,因子,1,因子,2,因子,3,FINS,0.61468,-0.19901,0.67766,PINS,0.30795,-0.18976,0.70573,BMI,0.72796,0.00352,0.50434,WC,0.76850,-0.01185,0.44926,SBP,0.06560,0.94944,-0.09848,DBP,0.04105,0.95242,-0.05673,TG,0.76565,-0.14737,-0.00467,HDL,-0.94916,-0.16047,-0.10582,FBG,0.13982,-0.65519,-0.13143,PBG,0.01195,-0.37847,-0.71218,方差贡献率,0.4067,0.2492,0.1014,累积方差,0.4067,0.6559,0.7572,14,研究结果,IGT,组,TG,HDL,FINS,BMI,WC,PINS,PBG,FBG,SBP,DBP,1,2,3,15,新诊断,DM,组,变量,因子,1,因子,2,因子,3,因子,4,FINS,-0.00335,0.14159,-0.11397,0.86475,PINS,-0.50761,-0.08615,0.00392,0.62025,BMI,-0.00275,0.74897,0.09590,0.32732,WC,0.08985,0.76849,0.12867,0.18351,SBP,0.06551,-0.13659,0.93111,0.08432,DBP,-0.12746,0.21508,0.75733,-0.29704,TG,-0.21380,0.66815,-0.16039,-0.30557,HDL,-0.31116,-0.51533,0.07781,0.03122,FBG,0.92229,0.11557,-0.03902,-0.05787,PBG,0.93796,-0.08737,0.02370,-0.01327,方差贡献率,0.2682,0.2033,0.1472,0.1036,累积方差,0.2682,0.4715,0.6186,0.7222,16,研究结果,新诊断,DM,组,FBG,PBG,PINS FINS,BMI,、,WC,TG,、,HDL,SBP,、,DBP,1,2,3,4,17,CHD,组,变量,因子,1,因子,2,因子,3,因子,4,FINS,0.75411,0.35167,-0.00353,-0.11093,PINS,0.74685,0.03896,-0.01939,0.15823,BMI,0.79305,-0.04203,0.08846,-0.23972,WC,0.75372,-0.16607,0.03146,-0.39796,SBP,0.06688,0.09685,0.89470,0.04950,DBP,-0.01053,-0.01844,0.91698,-0.00852,TG,0.30652,0.23684,0.02281,-0.67834,HDL,-0.00917,0.00323,0.06211,0.88406,FBG,-0.05872,0.93574,0.03994,-0.16222,PBG,0.13209,0.93079,0.04597,0.00688,方差贡献率,0.2945,0.1866,0.1632,0.1144,累计方差,0.2945,0.4811,0.6443,0.7588,18,研究结果,CHD,组,FINS,PINS,BMI,WC,FBG,PBG,SBP,DBP,HDL,TG,1,2,3,4,19,对象,方法,结果,讨论,20,讨论,包含“IR、肥胖的因子,方差奉献率最大,IR和肥胖是MS的,主要病理生理根底,不同人群获得因子构造不同，,但均包括了IR、肥胖、血脂,紊乱与高血压等指标,多数情况血压测量值,独立构成一个因子,MS,有共同的病理生理机制,复杂多种因素参与其中,血压在MS的发生开展中,的作用特殊,21,谢谢！,22,谢谢欣赏！,23,2021/11/5,谢谢观赏,