皮肤病学课件皮肌炎

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,皮肌炎,Dermatomyositis,温州医科大学附属第二医院,育英儿童医院,皮肤科,方姗,皮肌炎,1,目的与要求:,、掌握皮肌炎的病因及发病机制、临床表,现、诊断。,2、了解皮肌炎的组织病理、治疗。,目的与要求:,2,皮肤病学课件皮肌炎,3,Nail changes,Capillary Loop,Dilatation,Source: IMACS,Nail changes,4,皮肤病学课件皮肌炎,5,定义 Definition,是一种主要累积皮肤和横纹肌的自身免疫性疾病,以亚急性和慢性发病为主。,包括皮肤、肌肉两方面病变,也可表现单一病变,多见于40-60岁,男女之比约1:2,儿童期和4060岁两个发病高峰,定义 Definition,6,分类 Classification,多发性肌炎,皮肌炎,合并肿瘤的皮肌炎或多肌炎,儿童皮肌炎或多肌炎,合并其他结缔组织病皮肌炎或多肌炎,无肌病性皮肌炎,分类 Classification,7,病因 etiology,1、自身免疫,抗Jo-1、PL7抗体,2、感染,科萨奇病毒、EB病毒,3、肿瘤,鼻咽癌、乳腺癌、卵巢癌,4、遗传,HLA-B8等基因位点,病因 etiology,8,皮肤病学课件皮肌炎,9,皮肤病学课件皮肌炎,10,皮肤病学课件皮肌炎,11,皮肤病学课件皮肌炎,12,皮肤病学课件皮肌炎,13,皮肤病学课件皮肌炎,14,皮肤病学课件皮肌炎,15,皮肤病学课件皮肌炎,16,皮肤病学课件皮肌炎,17,皮肤病学课件皮肌炎,18,皮肤病学课件皮肌炎,19,皮肤病学课件皮肌炎,20,皮肤病学课件皮肌炎,21,皮肤病学课件皮肌炎,22,皮肤病学课件皮肌炎,23,皮肤病学课件皮肌炎,24,皮肤病学课件皮肌炎,25,皮肤病学课件皮肌炎,26,皮肤病学课件皮肌炎,27,皮肤病学课件皮肌炎,28,