皮肤性病学带状疱疹英文教学培训ppt课件

文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Definition Herpes zoster is caused by Varicella -Zoster virus (VZV),classically occurs unilaterally within the distribution of a sensory nerve,being characterized by clustered vesicles and considerable neuralgia.Definition 1文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Pathogen and Pathogenesis Pathogen Varicella-Zoster virus(VZV)is characterized by neurotropism and dermatotropism.Pathogen and Pathogenesis 2文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Pathogenesis VZV causes varicella in childhood,and establishes latency in sensory ganglia after the primary infection.VZV may replicate later in life,taking advantage of the decline in immune function,traveling down the sensory nerve into the skin,showing neuralgia and clustered vesicles.Pathogenesis 3文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Clinical manifestationsProdrome:l headache and feverl hyperaesthesial pain in the affected area.Clinical manifestations4文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Features of lesions The eruption presents as papules and erythema in the dermatome.Over a few days,crops of clustered red papules form in a discontinuous band and quickly evolve to clear vesicles surrounded by erythema.Features of lesions5文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。The eruption may have few lesions or reach total confluence in the dermatome.Lesions may become hemorrhagic,necrotic,or bullous.皮肤性病学带状疱疹英文教学培训ppt课件6文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。The vesicles slowly become pustulars,and rupture to form crusts,which separate in two to four weeks,often with scarring.The regional lymph nodes are enlarged and tender.7文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。ComplicationsPostherpetic neuralgia(PHN)The pain persists after the skin lesions have healed,with the same quality as that of acute zoster pain.a monthComplications8文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Ophthalmic Zoster Ocular involvement is most commonly in the form of uveitis and keratitis.Ophthalmic Zoster9文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Ramsay Hunt syndrome l Results from involvement of the facial and auditory nerves by the VZV.l The presenting features include:herpes auricularis,facial paralysis,and auditory symptoms.VZV.Herpetic inflammation of the geniculate ganglion is felt to be the cause of this syndrome.The presenting features include:herpes auricularis,facial paralysis,and auditory symptoms.Ramsay Hunt syndrome 10文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Incomplete herpes zoster There are may only neuralgia and papuloid lesions but with no blisters.皮肤性病学带状疱疹英文教学培训ppt课件11文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Disseminated Herpes Zosterl A generalized varicelliform eruption accompanying the segmental eruption.l It has been defined as more than 20 lesions outside the affected dermatome.l It occurs chiefly in old or debilitated individuals,especially in patients with malignancy and AIDS.Disseminated Herpes Zoster12文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Diagnosis and MisdiagnosisDiagnosis lTypical lesions:crops of clustered vesicles surrounded by erythema,forming in a discontinuous band,with enlarged regional lymph nodes.lThe distribution of a signal dorsal nerve root.l Obvious neuralgiaDiagnosis and Misdiagnosis13文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Misdiagnosis:Pain ususlly precedes the eruption by 3 or 4 days,sometimes it may be misdiagnosed to other diseases,depending on different part.Appendicitis Cholecystitis Angina pectorisMisdiagnosis:14文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。TreatmentlBed restlAntivirival therapy:acyclovir (ACV)0.2 5 times daily valacyclovir(VCV)1.0 3 times daily famciclovir(FCV)0.5 3 times daily for 7 daysTreatment15文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。lVitamin B:help to relief the inflammation of the involved nerve and relief the pain.TTFD 25mg tid VitB12 0.5mg im qdlAnalgesic:aspirin indomethacin Vitamin B:help to re16文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。lNerve blockslImproving immune function:transfer factor(TF)lSystemic corticosteroid therapy:prednisone 10mg tidlPhysical therapy lTopical therapy:5%sclNerve blocks17文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。In conclusion:l Definition Pathogenl Clinical manifestations Complicationsl Diagnosis and misdiagnosis TreatmentIn conclusion:18文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Definition Herpes zoster is caused by VZV,classically occurs unilaterally within the distribution of a sensory nerve,with the features of clustered vesicles and neuralgia.Definition 19文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Pathogen Varicella-Zoster virus(VZV)is characterized by neurotropism and dermatotropism.皮肤性病学带状疱疹英文教学培训ppt课件20文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Clinical manifestationsProdromeTypical lesionsDistributionNeuralgiaClinical manifestations21文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。ComplicationsPostherpetic neuralgia(PHN)Ophthalmic ZosterDisseminated Herpes ZosterRamsay Hunt syndromeComplicationsPostherpetic neur22文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Diagnosis and MisdiagnosisTreatmentl Bed restlAntivirival therapyl Vitamin Bl Analgesicl Nerve blocksDiagnosis and Misdiagnosis23文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。l Improving immune functionl Systemic corticosteroid therapy l Physical therapy l Topical therapy皮肤性病学带状疱疹英文教学培训ppt课件24文档仅供参考，不能作为科学依据，请勿模仿；如有不当之处，请联系网站或本人删除。Thank you皮肤性病学带状疱疹英文教学培训ppt课件25