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单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,单击此处编辑母版标题样式,Cerebrospinal Fluid(CSF)Examination,Outline,CSF:,colourless,liquid that flows through the four cerebral ventricles,subarachnoid space and spinal canal surrounding the,brain,and,spinal cord,.,CSF,cirlulation,communicate with blood circulation,Adult:90150ml,Newborn:10 60ml,blood brain barrier,AIMS,中枢神经感染性疾病的诊断与鉴别诊断。,脑血管疾病的诊断与鉴别诊断。,协助脑部肿瘤的诊断。,中枢神经系统疾病的治疗与疗效观察。,Contents of examination,General Properties,：,pressure,、,color,、,T,ransparency,、,Clots and film,Chemical Examination,：,protein,、,glucose,、,chloride,Microscopy,Bacteriological Examination,Pressure,General Properties,Adult(lying,):80180mmH,2,O,，,40-50 drips/min,children,：,40-100mmH,2,O,。,Increase,：,Intracranial,Inflammation,：,meningitis,cephalitis,myelitis,cerebral edema,cerebral hemorrhage,brain tumors,Extracranial,：,hypertension,congestive heart failure,Decrease:,CSF,circulation obstruction,loss or impairment in secretion,Color changes,Color of CSF,Conditions or causes,Clear,colorless,normal,Milky,With WBC increase,Pink to yellow,With blood,Yellow,Hyperbilirubinemia,Protein1.5g/L,Green,Purulent CSF,Brown to Black,Meningeal,melanoma,T,ransparency,Normal:Clear,colorless,Clear or Cloudy,：,Viral Meningitis,、,Epidemic Encephalitis B or Syphilis in CNS,Ground glass opacity,：,Tuberculous,Meningitis,Milky turbid,：,Purulent Meningitis,Clots and film,Normal:No clots or film in 24 hours,Purulent Meningitis:clots observed in 1-2 hours,Tuberculous,Meningitis:thin film cover after 1224 hours,S,ubarachnoid,obstruction:yellow,jelly,Protein,Qualitative,：,Pandy,test,：,-/,Quantitative,：,0.15,0.45g/L(,adult,lumbar,puncture),+,+,+,+,Chemical examination,Clinical significance,inflammation,：,PM:,TM:,VM:,Hemorrhage in cranial or subarachnoid,intracranial mass lesions,：,tumor,hematoma,multiple sclerosis,neurosyphilis,Glucose in CSF,Normal value:,Adult:2.54.5mmol/L,Child:3.14.5mmol/L,G,CSF,/G,P,：,0.30.9,Clinical significance,Inflammation,：,PM:,TM:,VM,：,normal,Intracranial tumor,neurosyphilis,Hypoglycemia,Chloride in CSF,Adult,：,120130mmol/L,TM,：，,102mmol/L,PM,：,102116mmol/L,。,H,ypochloremia,，,such as severe vomit,、,diarrhea,dehydration,Normal Value,RBC,：,none,WBC:,adult,：,0810,6,/L,child,：,01510,6,/L,Microscopic Examination,Clinical Significance,Infectious Diseases in CNS,PURULENT MENINGITIS,1000-2000,10,6,/L,，,segmented,neutrocyte,Tuberculous,Meningitis,500,10,6,/L,，,segment,neutrocytes,in early stage,and lymphocytes increase afterward,plasmocyte,also observed,Viral Meningitis,1000,10,6,/L,，,lymphocytes,Clinical Significance,Brain tumor,：,lymphocytes and tumor cells,Parasitic encephalopathy:,eosinophile,granulocyte,Hemorrhage:RBC,NORMAL,PM,TM,VM,SAH,Pressure mmH,2,O,70-180,或,Appearance,Clear,colorless,Milky,、,green,Ground Glass opacity,clear,bloody,Clots and film,no,clots,Thin film,No,jelly,protein,0.2-0.4g,Glucose,mmol,/L,2.5-4.5,Normal,Chloride,mmol,/L,119-129,Normal,Normal,Cells,No,neutrocytes,Neutrocytes,lymphocytes and plasma cells,lymphocytes,RBC,BACTERIALS,NO,pyogenic,tubercle bacillus,No,no,General concepts,serous membrane fluid:,pleural,effussion,peritoneum serous,pericardial effusion,Serous Membrane Fluid,Classification,Transudate,:non-inflammatory,Exudate,：,inflammatory,differential diagnosis of,transudate,or,exudate,Transudate,Exudate,causes,Increased capillary permeability,Infection,malignant cancer,Appearance,Light yellow,clear or cloudy,Bloody,purulent,milky turbid,gravity,1.018,clotting,-,+,Cells,100,10,6,/L,different cells,bacteriology,-,+,Total protein,30g/L,Rivalta,-,+,Glucose,3.3mmol/L,3.3mmol/L,Pleural fluid/,serumTP,0.5,Pleural fluid/,serumLDH,0.6,LDH,200IU,
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