会议海报 poster 11-10 Suya Xu-Jia

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,2013/11/10,#,Anatomical and hemodynamic evaluations of the heart and pulmonary arterial pressure,in healthy Han and Tibetan children residing at high altitude in China,Hai-Ying Qi,Ru-Yyan Ma,Li-Xia Jiang,Shu-Ping Li,Shu Mai,Hong Chen,Mei Ge,Mei-Ying Wang,Haining Liu,Yue-Hong Cai,Su-Ya Xu,Jia Li,Objectives,Altitude-hypoxia induces pulmonary arterial hypertension and altered cardiac morphology and function,which is little known in healthy children at high altitude.,Compare the cardiopulmonary measurements between the healthy children at 16m and those at 3700 m in China,and further compared these measurements between the Han and Tibetans at 3700m,Results,Comparison of anatomical and hemodynamic evaluations of the heart and pulmonary arterial pressure between the sea level and high altitude groups,Table 1.demographic variables,Table 2.pulmonary arterial pressure variables,Table 3.the right and left heart morphology,Methods,477 children(15 day-14 years)including 220 at 16m and 257 at 3700m.,Children were divided into 7 age groups(1m-6m-1y-3-6y-10y-14y).,Echocardiographic assessments of the cardiac morphology and function,and pulmonary arterial pressure were made.,Age,Altitude,PEP,(ms),AT,(ms),ET,(ms),PEP/AT,AT/ET,mPAP(mmHg),1 m,16 m,366,7815,20525,0.490.14,0.380.06,14.58.6,3700 m,4010,5215,19614,0.790.14,0.260.08,35.18.9,6 m,16 m,376,8211,22624,0.450.11,0.370.06,15.47.5,3700 m,5012,8021,21332,0.690.35,0.370.08,27.311.8,12 m,16 m,407,9213,23427,0.440.06,0.390.05,14.85.2,3700 m,5310,8319,23513,0.680.24,0.350.08,25.115.2,3 y,16 m,428,9715,26027,0.440.10,0.370.06,17.76.9,3700 m,4911,8119,23929,0.650.26,0.340.07,26.812.9,6 y,16 m,427,11519,28722,0.380.08,0.400.06,14.86.5,3700 m,4911,9617,26125,0.530.19,0.370.06,24.18.2,10 y,16 m,469,12325,30030,0.390.11,0.410.07,16.67.5,3700 m,5613,10416,27425,0.560.18,0.380.05,23.18.5,14 y,16 m,4910,13119,30125,0.380.10,0.440.06,15.35.8,3700 m,5912,11619,29525,0.520.15,0.390.06,23.37.8,Statistics,P,age,0.0001,0.0001,0.0001,0.38,0.0001,0.09,P,altitude,0.0001,0.0008,0.04,0.0001,0.11,1 m,16 m,19,3.51.2,515,0.210.04,991,14910,3700 m,13,3.10.6,504,0.200.02,915,14719,6 m,16 m,23,6.91.7,624,0.340.05,1000,14013,3700 m,7,6.90.9,633,0.350.02,895,12116,12 m,16 m,19,9.31.5,733,0.440.04,992,12312,3700 m,4,9.11.0,755,0.440.04,901,12421,3 y,16 m,26,11.72.0,856,0.530.06,991,11115,3700 m,14,11.12.5,828,0.510.08,904,10912,6 y,16 m,45,17.53.0,1067,0.720.09,992,10212,3700 m,44,16.63.1,1059,0.700.09,902,10216,10 y,16 m,50,25.25.5,1269,0.940.13,991,8616,3700 m,97,22.43.7,1227,0.870.10,913,9715,14 y,16 m,30,42.912.2,14523,1.360.25,1001,8211,3700 m,69,32.56.4,14010,1.130.15,912,7812,Statistics,P,age,0.0001,0.0001,0.0001,0.79,0.0001,P,altitude,0.80,0.99,0.82,0.0001,0.29,P,age*altitude,0.04,0.53,0.04,0.87,0.11,Table 4.The right and left ventricular systolic and diastolic functional variables and cardiac index,Conclusions,The cardiopulmonary developmental values in the Han and Tibetan children at high altitude provide references for the care of healthy children and the sick ones with cardiopulmonary diseases at high altitude.,Results,As compared to the,sea-level group,children at 3700m,had,Higher mPAP,Increasing dilatation of the right heart,Slower decrease in RV hypertrophy in 14 years(p0.20),Systolic and diastolic function of both ventricles significantly reduced,CI was higher(p0.05).,Age,Altitude,RA,(cm),RVd,(cm),RVOT,(cm),PA,(cm),RVAW,(cm),RVmass,(g),LA,(cm),LVd,(cm),LVs,(cm),AO,(cm),LVPWd,(cm),LVPWs,(cm),LVmass,(g),Right,Left,1 m,16 m,0.90.1,0.80.1,1.00.1,0.90.1,0.20.0,1.790.43,1.00.1,1.80.3,1.00.2,1.00.1,0.30.0,0.50.1,6.832.41,3700 m,0.90.1,0.70.1,1.00.1,1.00.1,0.20.1,1.400.40,0.90.1,1.80.1,1.10.1,1.00.1,0.20.1,0.50.1,5.781.71,6 m,16 m,1.00.1,0.90.1,1.20.1,1.10.1,0.20.0,2.200.34,1.20.1,2.30.3,1.10.3,1.20.1,0.30.0,0.60.1,10.212.65,3700 m,1.30.1,1.00.2,1.70.3,1.30.1,0.20.1,2.701.11,1.30.1,2.30.4,1.20.3,1.20.1,0.30.0,0.70.1,11.554.12,12 m,16 m,1.20.1,0.90.1,1.40.2,1.30.1,0.20.0,2.460.57,1.30.3,2.60.2,1.20.2,1.40.1,0.30.1,0.60.1,14.283.31,3700 m,1.20.2,1.10.2,1.70.2,1.50.2,0.20.0,2.930.55,1.40.3,2.50.1,1.40.1,1.40.1,0.30.0,0.70.1,12.180.41,3 y,16 m,1.30.1,1.00.2,1.50.1,1.40.1,0.20.0,2.690.79,1.50.1,2.80.3,1.50.2,1.50.1,0.30.1,0.70.1,17.374.37,3700 m,1.40.2,1.20.2,1.80.2,1.60.2,0.20.1,3.951.29,1.50.1,2.70.3,1.50.2,1.50.1,0.40.1,0.80.1,18.354.94,6 y,16 m,1.40.1,1.20.2,1.80.2,1.70.2,0.20.1,3.800.97,1.80.1,3.30.3,1.80.4,1.70.2,0.40.1,0.70.2,24.485.25,3700 m,1.60.2,1.20.2,1.90.2,1.80.1,0.20.1,4.071.27,1.70.2,3.10.3,1.80.2,1.70.2,0.40.1,0.80.1,23.905.87,10 y,16 m,1.50.2,1.30.2,1.90.2,1.80.2,0.20.0,5.001.48,1.90.2,3.60.4,2.00.3,1.90.2,0.40.1,0.90.1,35.259.58,3700 m,1.80.2,1.30.2,2.20.2,2.00.2,0.20.1,5.331.85,1.90.2,3.50.3,2.10.3,1.90.2,0.40.1,0.90.1,33.729.17,14 y,16 m,1.70.3,1.50.2,2.20.3,2.10.2,0.30.0,6.912.46,2.20.3,4.10.5,2.20.4,2.30.2,0.50.1,1.00.2,50.6915.95,3700 m,1.90.2,1.50.2,2.40.2,2.20.2,0.30.1,7.362.48,2.10.2,3.90.3,2.10.3,2.20.2,0.50.1,1.00.1,46.5310.39,Statis