资源描述
单击此处编辑母版文本样式,第二级,第三级,*,单击此处编辑母版标题样式,单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,Click to edit Master title style,Click to edit Master text styles,Second level,Third level,Fourth level,Fifth level,*,制药工程 专业英语 Unit 11,capsules,emulsion,syrup,tablet,suspension,ointment,cream,elixir,胶囊,乳剂,糖浆,片剂,混悬剂,软膏,霜剂,酒剂,The parenteral route of administration is important,in,treating medical emergencies,(,in which a subject is comatose or cannot swallow,), and,in,providing various types of maintenance therapy for hospitalized patients.,If patient self-administration cannot be achieved, the sales of the drug constitute only a small fraction of,what the market would be otherwise,.,The reasons for this preference are as follows. Tablets and capsules represent,unit dosage forms,in which,one usual dose,of the drug has been accurately placed.,By comparison, liquid oral dosage forms, such as syrups, suspensions, emulsions, solutions, and elixirs, are usually designed to,contain one dose of medication in 5 to 30 ml.,Properties,The objective of the design and manufacture of the compressed tablet is,to,deliver orally the correct amount of drug in the proper form,at or over,the proper time and,in,the desired location,and,to,have its chemical integrity protected to that point. Aside from the physical and chemical properties of the medicinal agent(s) to be formulated into a tablet, the actual physical design, manufacturing process, and complete chemical makeup of the tablet can have a profound effect on the efficacy of the drug(s) being administered.,A tablet (1) should be an elegant product having its own,identity,while being free of defects such as chips, cracks, discoloration, contamination, and the like; (2) should have the strength to withstand the rigors of mechanical shocks encountered in its production, packaging, shipping, and dispensing; and (3) should have the chemical and physical stability to maintain its physical attribute over time.,Pharmaceutical scientists now understand,that,various physical properties of tablets can undergo change under environmental or,stress,conditions, and,that,physical stability,through its effect on bioavailability in particular, can be of more significance and concern in some tablet systems than chemical stability.,9,Thank you,Thank You !,不尽之处,恳请指正!,
展开阅读全文