支气管哮喘英文版课件

单击此处编辑母版标题样式,单击此处编辑母版文本样式,第二级,第三级,第四级,第五级,*,*,Bronchial asthma,Department of respiration,Kong lingfei,Asthma i human killer/,Background of asthma,Prevalence in the world:1.6 hundred million,in China:1-3,in Shenyang:1.24%(1999),GINA:Global Initiative for Asthma(1994,WHO/HLBI,Bronchial asthmatic diagnosis guideline(1997,Chinese medical academy,Definitions of asthma,Chronic airway inflammation,Broncho-hyperresponsiveness BHR,Airflow limitation,Mechanism:allergy theory,antigen,antigen,atopy IgE antibody mast cells.,basophils,histamine,inflammatory mediaLTs,PAF,ECP,immediate asthmatic reaction,IAR,bronchial smooth muscle spasm,airway narrow,Mechanism:never-receptor disorder theory,adrenergic and cholinergic nerous systems,AC,non-adrenergic and non-cholinergic nerous systems,NANC,AC:al-receptor,MI,M3-receptors)excitement,NANC:PS-receptor,bronchial smooth muscle contraction,AC:receptor、M2-receptor,excitement,NANC:VIP receptor,bronchial smooth muscle dilation,asthmatic airway:al、M1、M3、PS/、M2、VP,Mechanism:airway inflammation theory,antigen,allergic airway inflammation AAI,ECP,MBP,inflammatory cells inflammatory mediaLTs,EOS,PAF,neutrophils,late asthmatic reaction.LAR,Tlymphocyte(Thi/Th2D),Th2 cytokine Il3、4、5,GM-CSFlgE,Differ mechanisms in acute and chronic asthma,acute,chronic,inflammation,inflammation,remodelling,bronchial contraction,inflammation cells,cell proliferation,mucous edema,epithelium injury,airway secretion,excellular base,aIrway,aIrway narrow,BHR,reversibility,symptoms,exacerbation,Other mechanisms:induced factors,Allergen:pollen,acarus,infection:virus or mycoplasmal infection,climate and physical and chemical factors,drugs:aspirin induced asthma,AIA,-receptor inhibitor,heredity,Gastroesophageal reflux disease GERD,Psychological,incretion factors,sports,Diagnosis standards of asthma,symptoms,signs,recovered ways,except other cardiac and pulmonary diseases,lung function examination untypical asthma,