高血压和肥胖ppt课件

Hypertension and Obesity in ChinaProfessors Chen Chunming&Zhao Wenhua(On behalf of the Working Group on Obesity in China,ILSI Focal Point in China),Chinese Center for Disease Control and Prevention,Beijing ChinaHypertension and Obesity in ChPart I:Hypertension risk at BMI and waist circumference(WC)levelsPart I:Hypertension risk at International Life Science Institute Focal Point in China(ILSI FP-China)established a Working Group on Obesity in China(WGOC)in 2000.WGOC organized a meta analysis on the data from 13 big scale cross-sectional survey since 1990,under a protocol for analysis data collected among 239,972 adults aged 20-70 were included.Data source and analysis International Life Science InsAnalysis on disease risks factors,such as high blood pressure,diabetes including fast blood glucose(FBG),serum cholesterol,HDL-C,triglycerides(TG),in relation to BMI and waist circumference(WC)was carried out.Meta analysis of cohort studies covered 4 data sets with 76,227 adult subjects was done,the end points are total mortality,mortality of coronary heart disease,stroke and cancer,as well as incidences of coronary heart disease events and stroke events.Part of the results is presented here.Analysis on disease risks factThe results on the prevalence of hypertension,and clustering of risk factors(high blood pressure,diabetes including fast blood glucose(FBG),serum cholesterol,HDL,triglycerides)and BMI or waist circumference(WC)was presented as follows.The results on the prevalence SEX12STANDARD RATE OF HBP%01020304050BMI1718192021222324252627282930BMI and high blood pressureMale MaleFemaleThe prevalence of hypertension increased with increasing levels of BMI.SEX12STANDARD RATE OF HBP%010SEX12RATE OF HBP%102030405060waist60708090100WC and high blood pressureMaleFemaleThe prevalence of hypertension increased with increasing levels of WCSEX12RATE OF HBP%102030405060SEX12STANDARD RATE OF RF=2%01020304050BMI1718192021222324252627282930BMI and risk factor clusteringMaleFemaleThe prevalence of clustering of risk factors increased with increasing levels of BMI.SEX12STANDARD RATE OF RF=2%0SEX12RATE OF RF=2%010203040506070waist60708090100WC and risk factor clusteringMaleFemaleThe prevalence of clustering of risk factors increased with increasing levels of WC.SEX12RATE OF RF=2%0102030405Population attributable risk percent(%)of hypertension at BMI levelsMale FemaleOR*PARP OR PARPBMI 24 3.69 45.9 2.76 38.4BMI 28 3.17 11.5 2.61 12.7*Age adjustedPopulation attributable risk pPopulation attributable risk%of hypertension beyond WC cutoffsOR*PARPMen WC85cm 3.44 41.3Women WC80cm 3.30 42.8*Age adjustedPopulation attributable risk%Part II:Correlation analysis of WC、BMI and blood pressurePart II:Correlation analysisData source and analysisA study was conducted in Anhui and Henan provinces in 1996 by Chen Junshi and Zhao Wenhua.Totally 11,815 rural residents aged 40-79 were surveyed and information included blood pressure,high,weight and waist circumference,diet and blood sample were collected.The relationship between WC、BMI and blood pressure was analyzed.Data source and analysisA studCorrelation analysis of WC、BMI and blood pressure(male)MaleBMIWCrprpBMI-0.6390.001WC0.6390.001-SBP0.1860.0010.1890.001DBP0.2530.0010.2320.001Correlation analysis of WC、BMIFemaleBMIWCrprpBMI-0.6370.001WC0.6370.001-SBP0.2330.0010.1980.001DBP0.3040.0010.2220.001Correlation analysis of WC、BMI and blood pressure(Female)FemaleBMIWCrprpBMI-0.6370.00Prevalence(%)of hypertension by BMI group(male)0102030405060 18 18-19-20-21-22-23-24-25-26-*BMI%HPBMI、WC and Prevalence of HypertensionPrevalence(%)of hypertension Prevalence(%)of hypertension by BMI group(Female)010203040506070 18 18-19-20-21-22-23-24-25-26-BMI%HP*Prevalence(%)of hypertension Prevalence(%)of hypertension by WC group(male)010203040506070 60 60-65-70-75-80-85-90-95-100-*Prevalence(%)of hypertension Prevalence(%)of hypertension by WC group(Female)0 0101020203030404050506060 60 60-65-70-75-80-85-90-95-100-*Prevalence(%)of hypertension Combination of BMI and WC in relation to hypertension prevalenceCombination of BMI and WC in r05101565-70-75-80-85-90-95-22-23-24-25-WC%HPBMICombination of BMI and WC in relation to hypertension prevalence(Male)05101565-70-75-80-85-90-95-22-Combination of BMI and WC in relation to hypertension prevalence(Female)05101565-70-75-80-85-90-95-22-23-24-25-WC%HPBMIWhen WC75cm,prevalence of hypertension increased significantly(P0.05).Combination of BMI and WC in rHypertension prevalence%at various WC levels with BMI 24（male）0510152065-70-75-80-85-90-95-WC24*Hypertension prevalence%at vHypertension prevalence%at various WC levels with BMI24（female）05101565-70-75-80-85-90-95-WC24*At BMI 24,WC 80(male)WC 75(female),prevalence or hypertension dramatically increased(p0.05 for all groups)Hypertension prevalence%at vPart III:Summary and Conclusion Data indicated application of Combination of BMI and WC will be the best predictor for hypertension risk,recommendation was made to set overweight cutoff at BMI 24;WC85 for men and 80cm for women as normal.Part III:Summary and ConclusiApplying the classification,overweight(BMI24)prevalence is 30-40%,if BMI could be controlled under 24,38-45%hypertension of this population,33-37%of diabetes,45-50%risk factor clustering may be prevented.If the 8-12%obesity population(BMI 28)could be treated,15-17%risk factor clustering could be prevented.Applying the classification,o高血压和肥胖ppt课件